Itinerary
- Day 1
Panama City
Optional Activities
- Visit Casco Viejo colonial town
- View Bridge of the Americas from ramparts
Landmarks Casco Viejo Bridge of the Americas 
- Day 2
Panama City
- Meals
- Breakfast
Included Activities
- Visit Miraflores Locks and Panama Canal
Optional Activities
- Explore Casco Viejo colonial district
Landmarks Miraflores Locks Panama Canal Casco Viejo - Day 3
Panama City to David
- Meals
- Breakfast
Included Activities
- Travel by public bus to Chiriqui Province
Landmarks Volcan Baru - Day 4
David to Bocas de Toro
- Meals
- Breakfast
Included Activities
- Town visit to Boquete
- Boat transfer to Isla Colon
Landmarks Boquete Isla Colon Bocas de Toro Parque Nacional Marino Isla Bastimentos 
- Day 5
Bocas de Toro
- Meals
- Breakfast
Optional Activities
- Snorkeling or diving offshore
- Boat trip around archipelago with dolphin spotting
- Visit Isla Bastimentos
- Visit Parque Nacional Marino Isla Bastimentos
- Explore beaches
Landmarks Isla Bastimentos Parque Nacional Marino Isla Bastimentos - Day 6
Bocas de Toro to Puerto Viejo Sarapiqui
- Meals
- Breakfast
Included Activities
- Boat return to mainland
- Full day drive to Puerto Viejo Sarapiqui
Landmarks Puerto Viejo Sarapiqui - Day 7
Puerto Viejo Sarapiqui to Arenal
- Meals
- Breakfast
Optional Activities
- Walk forest trails
- Boat ride along river
- Visit La Selva biological station
- Evening bathe in thermal baths
Landmarks La Selva Biological Station Arenal Volcano - Day 8
Arenal to Monteverde Cloud Forest
- Meals
- Breakfast
Included Activities
- Visit Arenal Volcano and national park
- Visit Monteverde Cloud Forest Reserve
Landmarks Arenal Volcano Lake Arenal Monteverde Cloud Forest Reserve 
- Day 9
Monteverde Cloud Forest
- Meals
- Breakfast
Included Activities
- Guided walk through cloudforest
Optional Activities
- Zip-wire canopy experience
- Suspension bridge walks
- Visit butterfly farm
- Visit orchid gardens
- Night walk through forest
Landmarks Monteverde Cloud Forest Reserve 
- Day 10
Monteverde to Rincon de la Vieja
- Meals
- Breakfast
Optional Activities
- Nature walks in national park
- Horseback ride to Oropendola Waterfall
- Walk to mud and hot springs
- Relax at eco lodge
Landmarks Rincon de la Vieja National Park Oropendola Waterfall 
- Day 11
Rincon de la Vieja
- Meals
- Breakfast
Included Activities
- Hike Las Pailas Trail
Optional Activities
- Nearby hiking trails
- Walk to mud and hot springs
- Canyon swing at Rio Blanco Canyon
- Horseback riding
- Biking excursions
Landmarks Las Pailas Trail Rio Blanco Canyon - Day 12
Rincon de la Vieja to Ometepe Island
- Meals
- Breakfast
Included Activities
- Ferry to Ometepe Island
Optional Activities
- Explore by local bus or truck
- Search for pre-Colombian petroglyphs
- Short walks on volcanic slopes
- Visit San Ramon Falls
- Relax on black sand beaches
Landmarks Ometepe Island Concepcion Volcano Maderas Volcano San Ramon Falls Lake Nicaragua 
- Day 13
Ometepe Island
- Meals
- Breakfast
Optional Activities
- Explore Ometepe Island
Landmarks Ometepe Island - Day 14
Ometepe Island to Granada
- Meals
- Breakfast
Included Activities
- Return ferry from Ometepe Island
- City tour of Granada
- Visit Parque Central
- Visit Monument to war of independence
- Visit San Francisco convent
Landmarks Granada Mombacho Volcano Parque Central San Francisco Convent 
- Day 15
Granada
- Meals
- Breakfast
Optional Activities
- Walk Granada's narrow lanes and alleyways
- Visit Las Isletas by boat or sea kayak
- Zip-line through forest canopy
- Explore surrounding agricultural area
- Visit Mombacho Cloud Forest
Landmarks Las Isletas Mombacho Volcano Mombacho Cloud Forest - Day 16
Granada to Leon
- Meals
- Breakfast
Included Activities
- Visit Masaya volcano
- Walking tour of Leon
- Visit Plaza del las Armas
- Visit Cathedral
- View Sandinista Murals
- Visit Ruben Dario Park
Optional Activities
- Short tour of Managua
Landmarks Masaya Volcano Managua Leon Plaza del las Armas Leon Cathedral Ruben Dario Park - Day 17
Leon to Tegucigalpa
- Meals
- Breakfast
Optional Activities
- Summit Cerro Negro volcano
- Relax at Las Penitas Beach
- Visit San Juan Venado Mangrove Reserve
Landmarks Cerro Negro Las Penitas Beach San Juan Venado Mangrove Reserve Tegucigalpa - Day 18
Tegucigalpa to Roatan
- Meals
- Breakfast
Included Activities
- Domestic flight to Bay Islands
Landmarks Bay Islands Roatan 
- Day 19
Roatan
- Meals
- Breakfast
Optional Activities
- Scuba diving
- Snorkeling offshore reefs
- Hire boats and kayaks
- Go fishing
- Spot macaws, toucans, and parrots
- Relax at Sandy Bay resort
- Visit nearby botanical gardens
Landmarks Sandy Bay - Day 20
Roatan to Copan Ruinas
- Meals
- Breakfast
Included Activities
- Full day travel to Copan Ruinas
Landmarks San Pedro Sula Copan Ruinas 
- Day 21
Copan Ruinas
- Meals
- Breakfast
Included Activities
- UNESCO World Heritage Site tour with local guide
- Visit Great Plaza
- View Hieroglyphic Stairway
Optional Activities
- Visit site museum
- Visit nearby hot springs
- Visit Macaw Mountain
Landmarks Copan Ruinas Great Plaza Hieroglyphic Stairway Macaw Mountain - Day 22
Copan Ruinas to Antigua
- Meals
- Breakfast
Included Activities
- Orientation tour of Antigua
- Walking tour of colonial city
Landmarks Antigua Guatemala Agua Volcano Fuego Volcano Acatenango Volcano - Day 23
Antigua
- Meals
- Breakfast, Breakfast
Optional Activities
- Explore Antigua's churches and colonial buildings
- Shop in Antigua's markets
- Visit Mayan site Iximche
- Full-day trip to Tikal (includes domestic flight from Guatemala City to Flores)
Landmarks Antigua Guatemala Iximche Tikal - Day 24
Antigua
- Meals
- Breakfast
Optional Activities
- Day trip to Lake Atitlan and Panajachel
- Visit Guatemala City
- Visit Ixchel Museum
- Visit Palacio Nacional
Landmarks Lake Atitlan Panajachel Guatemala City Ixchel Museum Palacio Nacional - Day 25
Antigua Guatemala
- Meals
- Breakfast
