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From
US $20,762 per person

Best of South America with Amazon Cruise 2026 - Santiago to Iquitos, 2027/28 - Rio de Janeiro to Iquitos (2027)

22 days
•
From Rio de Janeiro to Iquitos
4.2 (27 reviews)
  • Aerial vista over a bay lined with city buildings with Sugarloaf Mountain rising above scattered islands.
  • Aerial panorama of a winding chocolate-colored river snaking through dense rainforest.
  • Powerful curtain of water cascading over lush green cliffs with mist rising under bright blue sky.
  • Historic cathedral lit by warm evening lights amid swaying palms and city bustle.
  • Modern skyline with the tallest glass tower rising above a sprawling sunny city backed by distant Andes.
    View all
  • Crowded golden-sand beach with turquoise waves and dramatic green mountains backing a lively seaside city.
From
US $
+ $3,101 additional upfront costs

Price based on Cheapest Room

Price based on Shared Room

Price based on Private Single Room

Price based on Private Double Room

Select departure month

Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
1 Adult2 Adults, 1 Child2 Children

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0

Best price guarantee Learn More

Plan your adventure:
Operator
APT
Ancient Wonders
Walk among ruins, temples, and timeless landmarks
Group Tour
Join a group and forge lifelong friendships
Fully Guided
An experienced guide will be with you for the entire tour
Low Intensity
Travelers can expect some light physical activities
Guided in English
Group Size 1 - 200
Ages 8+
Image of a map showing the route of the tour

Itinerary

  1. Intro

    Introduction

  2. Day 1

    Rio de Janeiro

    Rio de Janeiro
    Meals
    Dinner (Welcome dinner at hotel)
    Accommodation
    Hotel (Copacabana Palace)
    Landmarks
    Copacabana Beach
    Itinerary Image 1Itinerary Image 2
  3. Day 2

    Rio de Janeiro

    Rio de Janeiro
    Meals
    Lunch (Brazilian barbecue fare at a local restaurant)
    Accommodation
    Hotel (Copacabana Palace)

    Included Activities

    • Visit to Corcovado and Christ the Redeemer
    • Cable car to Sugarloaf Mountain
    Landmarks
    Christ the Redeemer
    Corcovado Mountain
    Sugarloaf Mountain
  4. Day 3

    Rio de Janeiro

    Rio de Janeiro
    Accommodation
    Hotel (Copacabana Palace)

    Included Activities

    • Freedom of Choice - Jeep Tour of Santa Teresa
    • Freedom of Choice - Guanabara Bay Boat Tour
    Landmarks
    Santa Teresa
    Guanabara Bay
  5. Day 4

    Rio de Janeiro to Iguazú Falls

    Rio de Janeiro to Iguazú Falls
    Meals
    Lunch
    Accommodation
    Hotel (Iguazú Falls)

    Included Activities

    • Leisurely walk between viewing platforms at Iguazú Falls
    • Jet Boat Safari (Freedom of Choice)
    • Helicopter Ride (Freedom of Choice)
    Landmarks
    Iguazú Falls
  6. Day 5

    Iguazú Falls

    Iguazú Falls
    Meals
    Lunch, Dinner
    Accommodation
    Hotel (Iguazú Falls)

    Included Activities

    • Rainforest Ecological Train and viewing platforms
    • Walking path to Devil's Throat
    • Wine Tasting with cheese pairings (Signature Experience)
    Landmarks
    Iguazú Falls
    Devil's Throat
  7. Day 6

    Iguazú Falls to Buenos Aires

    Iguazú Falls to Buenos Aires
    Meals
    Dinner (Tango demonstration and tapas)
    Accommodation
    Hotel (Buenos Aires)

    Included Activities

    • Tango Demonstration and Tapas (Signature Experience)
    Landmarks
    Recoleta
  8. Day 7

    Buenos Aires

    Buenos Aires
    Accommodation
    Hotel (Buenos Aires)

    Included Activities

    • Guided discovery of La Boca
    • Guided discovery of Palermo
    • Visit to La Recoleta Cemetery

    Optional Activities

    • Dinner at Fogón Asado
    • Dinner at Fervor
    • Dinner and Tango Show
    Landmarks
    La Boca
    Palermo
    La Recoleta Cemetery
  9. Day 8

    Buenos Aires

    Buenos Aires
    Accommodation
    Hotel (Buenos Aires)

    Included Activities

    • Tigre Cruise (Freedom of Choice)
    • Parisian Walking Tour (Freedom of Choice)
    • Teatro Colón Tour (Freedom of Choice)
    Landmarks
    Tigre
    Plaza San Martín
    Teatro Colón
    Paraná Delta
  10. Day 9

    Buenos Aires to Santiago

    Buenos Aires to Santiago
    Meals
    Dinner
    Accommodation
    Hotel (The Ritz-Carlton)
    Landmarks
    Andes Mountains
    Itinerary Image 1Itinerary Image 2
  11. Day 10

    Santiago

    Santiago
    Accommodation
    Hotel (The Ritz-Carlton)

    Included Activities

    • Guided discovery of Santiago

    Optional Activities

    • Dinner at Liguria Lastarria
    • Dinner at Ambrosia
  12. Day 11

    Santiago to Valparaíso

    Santiago to Valparaíso
    Meals
    Lunch (Lunch at a local vineyard)
    Accommodation
    Hotel (The Ritz-Carlton)

    Included Activities

    • Valparaíso Funicular Ride (Signature Experience)
    • Exploration of historic quarter
    • Lunch at local vineyard
    Landmarks
    Valparaíso
  13. Day 12

    Santiago to Lima

    Santiago to Lima
    Meals
    Dinner
    Accommodation
    Hotel (InterContinental Real Lima Miraflores)
  14. Day 13

    Lima

    Lima
    Meals
    Lunch (Traditional lunch at private hacienda)
    Accommodation
    Hotel (InterContinental Real Lima Miraflores)

    Included Activities

    • Guided discovery of Lima's historic centre
    • Peruvian Paso Horse Show at private hacienda (Signature Experience)
    • Traditional lunch at hacienda
    • Visit to Pachacamac ruins
    Landmarks
    Lima historic centre
    Pachacamac
  15. Day 14

    Lima to Sacred Valley

    Lima to Sacred Valley
    Meals
    Breakfast, Lunch (Farm-to-table lunch at Hacienda Sarapampa with views of Andes mountains and surrounding valleys)
    Accommodation
    Hotel (Tambo del Inka)

    Included Activities

    • Flight to Cusco
    • Hacienda Sarapampa Lunch at working corn farm (Signature Experience)
    Landmarks
    Cusco
    Sacred Valley
  16. Day 15

    Sacred Valley - Maras - Moray

    Sacred Valley - Maras - Moray
    Meals
    Lunch (Traditional lunch with Misminay community, views of Andes mountains and surrounding valleys), Dinner
    Accommodation
    Hotel (Tambo del Inka)

    Included Activities

    • Traditional Weaving Demonstration with Misminay community (Signature Experience)
    • Traditional lunch with Andean views
    • Salt Mines of Maras (Signature Experience)
    • Moray archaeological site visit
    Landmarks
    Salt Mines of Maras
    Moray
  17. Day 16

    Sacred Valley to Machu Picchu

    Sacred Valley to Machu Picchu
    Meals
    Lunch (Gourmet Andean-inspired lunch on board Inca Rail First Class train), Dinner
    Accommodation
    Hotel (Sumaq Machu Picchu Hotel)

    Included Activities

    • Inca Rail First Class Machu Picchu Train with gourmet Andean-inspired lunch (Signature Experience)
    • Locally guided exploration of Machu Picchu
    Landmarks
    Machu Picchu
    Aguas Calientes
  18. Day 17

    Machu Picchu to Cusco

    Machu Picchu to Cusco
    Meals
    Breakfast, Lunch (Lunch at local restaurant)
    Accommodation
    Hotel (JW Marriott El Convento Cusco or similar)

    Included Activities

    • Free time in Aguas Calientes
    • PeruRail Vistadome train return journey
    • Lunch at local restaurant
    Landmarks
    Aguas Calientes
    Cusco
  19. Day 18

    Cusco

    Cusco
    Meals
    Breakfast, Dinner (Farewell dinner at MAP Café in the central courtyard of the Museum of Pre-Columbian Art)
    Accommodation
    Hotel (JW Marriott El Convento Cusco or similar)

    Included Activities

    • Guided discovery of Cusco including Plaza de Armas
    • Peruvian Cooking Class (Freedom of Choice)
    • Sacsayhuamán Citadel Visit (Freedom of Choice)
    Landmarks
    Plaza de Armas
    Sacsayhuamán
    Museum of Pre-Columbian Art
  20. Day 19

    Iquitos - Amazon Cruise

    Iquitos - Amazon Cruise
    Meals
    Lunch (Boxed lunch during coach journey), Dinner (Three-course dinner on board)
    Accommodation
    Hotel (Amazon River Basin)

    Included Activities

    • Coach transfer to Nauta with rainforest commentary
    • Tender boat to Delfin III
    • Skiff exploration of Marañón River at dusk
    • Three-course dinner on board
    Landmarks
    Iquitos
    Marañón River
  21. Day 20

    Amazon Cruise

    Amazon Cruise
    Meals
    Breakfast, Lunch, Dinner
    Accommodation
    Hotel (Amazon River Basin)

    Included Activities

    • Meeting with local shaman and traditional medicine discussion
    • Kayak excursion along calmer tributary
    • Wildlife watching including monkeys and pink river dolphins
    Landmarks
    Amazon River
  22. Day 21

    Amazon Cruise

    Amazon Cruise
    Meals
    Breakfast, Lunch, Dinner
    Accommodation
    Hotel (Amazon River Basin)

    Included Activities

    • Skiff excursion on Nauta Caño with fishing and wildlife spotting
    • Visit to local community
    • Rainforest trail walk at Nauta Caño
    • Visit to Marañón and Ucayali rivers confluence
    Landmarks
    Nauta Caño
    Marañón River
    Ucayali River
  23. Day 22

    Iquitos

    Iquitos
    Meals
    Breakfast

    Included Activities

    • Tropical Amazon Aquarium visit
    Landmarks
    Tropical Amazon Aquarium
    Iquitos Airport

Want to read it later?

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What's Included

Expand All
  • Accommodation
  • Guide
  • Meals
  • Transport

What's Not Included

  • Flights
  • Insurance
  • Additional Services

Where You'll Stay

All accommodations are subject to change

  • Copacabana Palace

    Hotel
    Days 1, 2, 3

  • Iguazú Falls

    Hotel
    Days 4, 5

  • Buenos Aires

    Hotel
    Days 6, 7, 8

  • The Ritz-Carlton

    Hotel
    Days 9, 10, 11

  • InterContinental Real Lima Miraflores

    Hotel
    Days 12, 13

  • Tambo del Inka

    Hotel
    Days 14, 15

  • Sumaq Machu Picchu Hotel

    Hotel
    day 16

  • JW Marriott El Convento Cusco or similar

    Hotel
    Days 17, 18

  • Amazon River Basin

    Hotel
    Days 19, 20, 21

Operated by

APT

Response time
within 1 day
Response rate
60%
Cancellation policy
Learn more

Reviews About This Operator

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Dates & Prices

Select departure month

Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
1 Adult2 Adults, 1 Child2 Children

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0
Upcoming departures
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Ends in0d0h34m36s
  • From Tuesday
    13 Apr, 2027
    To Tuesday
    4 May, 2027
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  • From Tuesday
    29 Jun, 2027
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    20 Jul, 2027
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  • From Tuesday
    27 Jul, 2027
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    17 Aug, 2027
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  • From Tuesday
    2 Nov, 2027
    To Tuesday
    23 Nov, 2027
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  • 3 Other Unavailable Departures

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Trip essentials

Good to know

Tour ID: 347314

The practical details for your trip across Brazil, Argentina, Chile and Peru: money, plugs and flexible ways to pay, all in one place.

Have a question? Chat with a travel expert

  • Pay in installments

    Spread the cost in interest-free biweekly installments of $1,610.

  • Deposit only

    Book now with just a $750 deposit. The remaining balance is due 120 days before departure.

  • 4 local currencies

    You’ll encounter Argentine Peso in Argentina, Brazilian Real in Brazil, Chilean Peso in Chile, Sol in Peru.

  • Plug types I, C, N, L, A

    You’ll need an adapter for these sockets in Brazil, Argentina, Chile and Peru.

  • Currencies

    $
    Argentine Peso

    Argentina

    R$
    Brazilian Real

    Brazil

    $
    Chilean Peso

    Chile

    S/.
    Sol

    Peru

  • Plugs & adapters

    As a traveler from USA, Canada you will need an adaptor for types I, C, N, L. As a traveler from England, South Africa you will need an adaptor for types I, C, N, L, A. As a traveler from Australia, New Zealand you will need an adaptor for types C, N, L, A.

    • Type I

      Only used in Argentina

    • Type C

      Only used in Brazil and Peru

    • Type N

      Only used in Brazil

    • Type L

      Only used in Chile

    • Type A

      Only used in Peru

  • Visa

    Whether you need a visa depends on your nationality and how long you stay. We can’t process visas for you, but here’s a quick indication for this trip.

    This is only an indication. Visa rules depend on your passport, trip length and purpose. Always confirm with the official embassy or consulate before you travel.

  • Payment information

    Pay now
    A $750 deposit
    Balance due
    120 days before departure
    Installments
    Interest-free, every two weeks
    Currency
    USD
    Booking fee
    None

    Book now with just a $750 deposit and pay the rest later. The remaining balance is due 120 days before departure, charged automatically to your card, or you can split it into interest-free biweekly installments of $1,610 at checkout. Everything is charged in USD, and TourRadar never adds a booking fee. Any trip departing before February 3rd, 2027 will need to be paid in full at checkout.

    Accepted for APT tours

    • Visa
    • Maestro
    • Mastercard
    • American Express
    • PayPal

    TourRadar does NOT charge you an extra fee for using any of these payment methods.

  • Best price guarantee

    Found a lower price for the same tour elsewhere? We work directly with every tour operator, so we can match it.

    How it works

    1. Find a lower price

      Spot the same tour cheaper on another site or agency.

    2. Send us the quote

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    3. We match it

      If the quote qualifies, you book with us at that price.

    Your quote needs

    • Same tour and operator
    • Same start and end dates
    • Same number of travelers
    • Same inclusions and destinations
    • Same booking and cancellation terms, in the same currency
    • A link to the site or agency offering it

    What doesn’t count

    • Quotes issued more than 24 hours ago
    • Cash back or loyalty program rebates
    • Itineraries that are similar but not identical
    • Similar tours run by a different operator
    • Bookings already confirmed on TourRadar

    Every new booking also counts toward your , which unlocks extra savings.

  • Cancellation Policy

    Cancellation terms may vary per tour. Please check for the full cancellation policy here.

    Checking the cancellation terms for this tour…

    Your money is protected. TourRadar is an authorized agent of APT, and we handle payments so you don’t have to. Payment is securely transferred to the operator based on your departure date.

  • Insurance

    Our travel protection from our award-winning partner, XCover, means you and your travel companions can book with peace of mind knowing there’s protection available in case your trip doesn’t go to plan. At checkout you will be able to select between different options in case you or the tour are eligible for insurance. In case no option is available, you are always able to purchase travel insurance outside of TourRadar.

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  • Accessibility

    Some tours are not suitable for mobility-restricted traveler, however, some operators may be able to accommodate special requests. For any enquiries, you can contact our customer support team, who are ready and waiting to help you.

  • People also viewed

From
US $
+ $3,101 additional upfront costs

Price based on Cheapest Room

Price based on Shared Room

Price based on Private Single Room

Price based on Private Double Room

Select departure month

Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
1 Adult2 Adults, 1 Child2 Children

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0

Best price guarantee Learn More

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AdultsAges 18 or above

2

ChildrenUnder 18

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Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec