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2026

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2027

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Who is travelling?

Who is travelling?

AdultsAges 18 or above

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0
From
US $22,698 per person

Best of South America with Amazon Cruise 2026 - Santiago to Iquitos, 2027/28 - Rio de Janeiro to Iquitos (2028)

22 days
From Rio de Janeiro to Iquitos
4.1
26 traveler reviews
From
US $
+ $3,177 additional upfront costs

Price based on Cheapest Room

Price based on Shared Room

Price based on Private Single Room

Price based on Private Double Room

Select Date

Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
1 Adult2 Adults, 1 Child2 Children

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0
Save and compare this adventure

Best price guarantee Learn More

Plan your adventure:
Explorer
Curated to ignite your sense of adventure
Fully Guided
An experienced guide will be with you for the entire tour
Low Intensity
Travelers can expect some light physical activities
Guided in English
Group Size 1 - 200
Ages 8+
Image of a map showing the route of the tour

Itinerary

  1. Day 1

    Rio de Janeiro

    Meals
    Dinner (Welcome dinner at hotel)
    Accommodation
    Hotel (Copacabana Palace)

    Included Activities

    • Welcome dinner at hotel
    Landmarks
    Copacabana Beach
    Itinerary Image 1Itinerary Image 2
  2. Day 2

    Rio de Janeiro

    Accommodation
    Hotel (Copacabana Palace)

    Included Activities

    • Visit to Corcovado and Christ the Redeemer
    • Cable car ride to Sugarloaf Mountain summit
    • Sunset drink at Sugarloaf Mountain

    Optional Activities

    • Lunch at local restaurant featuring Brazilian barbecue
    Landmarks
    Christ the Redeemer
    Corcovado
    Sugarloaf Mountain
  3. Day 3

    Rio de Janeiro

    Accommodation
    Hotel (Copacabana Palace)

    Included Activities

    • Freedom of Choice sightseeing activity

    Optional Activities

    • Jeep tour through Tijuca National Park on open-top jeep
    • Guanabara Bay boat tour (half-day)
    Landmarks
    Tijuca National Park
    Guanabara Bay
  4. Day 4

    Rio de Janeiro to Iguazú Falls

    Accommodation
    Hotel (Iguazú Falls)

    Included Activities

    • Flight to Iguazú Falls
    • Panoramic walk between viewing platforms at Iguazú Falls
    • Signature Experience at Gran Melia Iguazú

    Optional Activities

    • Jet boat safari at Iguazú Falls
    • Helicopter ride over Iguazú Falls
    Landmarks
    Iguazú Falls
    Itinerary Image 1Itinerary Image 2Itinerary Image 3
  5. Day 5

    Iguazú Falls

    Meals
    Dinner (Wine tasting with cheese pairings)
    Accommodation
    Hotel (Iguazú Falls)

    Included Activities

    • Rainforest Ecological Train to Argentinian side of Iguazú Falls
    • Walkways and viewpoints including Devil's Throat
    • Signature Experience: Wine tasting with cheese pairings
    Landmarks
    Iguazú Falls
    Devil's Throat
  6. Day 6

    Iguazú Falls to Buenos Aires

    Meals
    Dinner (Tango demonstration and authentic tapas)
    Accommodation
    Hotel (Buenos Aires)

    Included Activities

    • Flight to Buenos Aires
    • Signature Experience: Tango demonstration and tapas
    Landmarks
    Recoleta
  7. Day 7

    Buenos Aires

    Accommodation
    Hotel (Buenos Aires)

    Included Activities

    • Guided discovery of Buenos Aires including La Boca, Palermo, and La Recoleta Cemetery

    Optional Activities

    • Dinner at Fogón Asado featuring Argentine barbecued meats
    • Dinner at Fervor steakhouse with grilled meats and seafood
    • Dinner and tango show with Argentine dishes
    Landmarks
    La Boca
    Palermo
    La Recoleta Cemetery
  8. Day 8

    Buenos Aires

    Accommodation
    Hotel (Buenos Aires)

    Included Activities

    • Freedom of Choice activity

    Optional Activities

    • Tigre cruise along rivers and canals of Paraná Delta
    • Parisian walking tour of Buenos Aires including Plaza San Martín and Plazoleta Pellegrini
    • Teatro Colón tour of iconic opera house
    Landmarks
    Tigre
    Paraná Delta
    Plaza San Martín
    Teatro Colón
  9. Day 9

    Buenos Aires to Santiago

    Meals
    Dinner
    Accommodation
    Hotel (The Ritz-Carlton)

    Included Activities

    • Flight to Santiago
    • Dinner
  10. Day 10

    Santiago

    Accommodation
    Hotel (The Ritz-Carlton)

    Included Activities

    • Guided discovery of Santiago

    Optional Activities

    • Dinner at Liguria Lastarria featuring empanadas, Chilean-style tuna tartare, pichanga, cocktails, wine and beer
    • Dinner at Ambrosia blending Chilean and French cuisine including ceviche
  11. Day 11

    Santiago to Valparaíso

    Meals
    Lunch (Lunch at local vineyard)
    Accommodation
    Hotel (The Ritz-Carlton)

    Included Activities

    • Exploration of Valparaíso historic quarter
    • Funicular ride with views of Valparaíso
    • Lunch at local vineyard
    Landmarks
    Valparaíso
  12. Day 12

    Santiago to Lima

    Meals
    Dinner
    Accommodation
    Hotel (InterContinental Real Lima Miraflores)

    Included Activities

    • Flight to Lima
    • Dinner
    Itinerary Image 1Itinerary Image 2
  13. Day 13

    Lima

    Meals
    Lunch (Traditional fare at private hacienda)
    Accommodation
    Hotel (InterContinental Real Lima Miraflores)

    Included Activities

    • Guided discovery of Lima's historic centre
    • Signature Experience at private hacienda with traditional lunch and Peruvian Paso horse show
    • Visit to Pachacamac ruins
    Landmarks
    Pachacamac
  14. Day 14

    Lima to Sacred Valley

    Meals
    Breakfast, Lunch (Farm-to-table lunch at working corn farm)
    Accommodation
    Hotel (Tambo del Inka)

    Included Activities

    • Flight to Cusco
    • Signature Experience: Hacienda Sarapampa farm-to-table lunch at working corn farm
  15. Day 15

    Sacred Valley - Maras - Moray

    Meals
    Lunch (Traditional lunch with views of Andes mountains and surrounding valleys), Dinner
    Accommodation
    Hotel (Tambo del Inka)

    Included Activities

    • Signature Experience: Traditional weaving demonstration with Misminay community and traditional lunch
    • Signature Experience: Salt Mines of Maras and Moray Terraces
    • Guided exploration of Salt Mines of Maras
    • Visit to Moray archaeological site
    Landmarks
    Salt Mines of Maras
    Moray
  16. Day 16

    Sacred Valley to Machu Picchu

    Meals
    Lunch (Gourmet Andean-inspired lunch on Inca Rail First Class train), Dinner
    Accommodation
    Hotel (Sumaq Machu Picchu Hotel)

    Included Activities

    • Signature Experience: Inca Rail First Class Machu Picchu Train with gourmet Andean-inspired lunch
    • Guided exploration of Machu Picchu with local guide
    • Dinner at hotel
    Landmarks
    Machu Picchu
  17. Day 17

    Machu Picchu to Cusco

    Meals
    Lunch (Lunch at local restaurant)
    Accommodation
    Hotel (JW Marriott El Convento Cusco or similar)

    Included Activities

    • Train journey on PeruRail Vistadome train back to Sacred Valley
    • Lunch at local restaurant
    • Transfer to Cusco
    Landmarks
    Aguas Calientes
  18. Day 18

    Cusco

    Meals
    Dinner (Farewell dinner at MAP Café in Museum of Pre-Columbian Art)
    Accommodation
    Hotel (JW Marriott El Convento Cusco or similar)

    Included Activities

    • Guided discovery of Cusco including Plaza de Armas
    • Freedom of Choice activity
    • Farewell dinner at MAP Café

    Optional Activities

    • Peruvian cooking class with traditional dishes and ingredients
    • Sacsayhuamán citadel visit with 15th-century Incan dry-stone walls
    Landmarks
    Plaza de Armas
    Sacsayhuamán
  19. Day 19

    Cusco to Iquitos - Amazon Cruise

    Meals
    Lunch (Boxed lunch en route to Nauta), Dinner (Three-course dinner on board Delfin III)
    Accommodation
    Hotel (Amazon River Basin)

    Included Activities

    • Flight to Iquitos via Lima
    • Coach transfer through rainforest to Nauta
    • Tender boat transfer to Delfin III
    • Skiff exploration along Marañón River at dusk
    • Three-course dinner on board
    Landmarks
    Marañón River
  20. Day 20

    Amazon Cruise

    Meals
    Lunch
    Accommodation
    Hotel (Amazon River Basin)

    Included Activities

    • Meeting with local shaman and traditional medicine education
    • Kayak exploration along tributary
    • Wildlife observation - birdlife, monkeys, pink river dolphins
    Landmarks
    Marañón River
  21. Day 21

    Amazon Cruise

    Accommodation
    Hotel (Amazon River Basin)

    Included Activities

    • Skiff excursion along Nauta Caño with fishing and wildlife spotting
    • Visit to local community
    • Rainforest trail walk at Nauta Caño
    • Visit to confluence of Marañón and Ucayali rivers
    Landmarks
    Nauta Caño
    Marañón River
    Ucayali River
  22. Day 22

    Depart Iquitos

    Included Activities

    • Disembarkation from Delfin III
    • Visit to Tropical Amazon Aquarium with over 60 species of tropical fish
    Landmarks
    Tropical Amazon Aquarium

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What's Included

Expand All
  • Accommodation
  • Guide
  • Meals
  • Additional Services
  • Transport

What's Not Included

  • Flights
  • Insurance
  • Additional Services

Where You'll Stay

All accommodations are subject to change

Operated by

APT

Response time
within 1 day
Response rate
63%
Cancellation policy

Reviews About This Operator

Dates & Availability

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Select Date

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2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
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Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
1 Adult2 Adults, 1 Child2 Children

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0
Upcoming departures
  • From Tuesday
    8 Feb, 2028
    To Tuesday
    29 Feb, 2028
    Not available in your region
  • From Tuesday
    7 Mar, 2028
    To Tuesday
    28 Mar, 2028
    Not available in your region
  • From Tuesday
    2 May, 2028
    To Tuesday
    23 May, 2028
    Not available in your region
  • From Tuesday
    13 Jun, 2028
    To Tuesday
    4 Jul, 2028
    Not available in your region
  • From Tuesday
    25 Jul, 2028
    To Tuesday
    15 Aug, 2028
    Not available in your region
  • From Tuesday
    22 Aug, 2028
    To Tuesday
    12 Sep, 2028
    Not available in your region
  • From Tuesday
    5 Sep, 2028
    To Tuesday
    26 Sep, 2028
    Not available in your region
  • 6 Other Unavailable Departures

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From
US $
+ $3,177 additional upfront costs

Price based on Cheapest Room

Price based on Shared Room

Price based on Private Single Room

Price based on Private Double Room

Select Date

Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
1 Adult2 Adults, 1 Child2 Children

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0
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Good to Know

Tour ID: 347312

  • Currencies
    $
    Argentine Peso
    Argentina
    R$
    Brazilian Real
    Brazil
    $
    Chilean Peso
    Chile
    S/.
    Sol
    Peru
  • Plugs & Adapters

    As a traveler from USA, Canada, England, South Africa you will need an adaptor for types I, L. As a traveler from Australia, New Zealand you will need an adaptor for type L.

    Type I
    Argentina
    Type L
    Chile
  • Vaccines
    • These are only indications, so please visit your doctor before you travel to be 100% sure.
    • Typhoid - Recommended for Argentina.Brazil.Chile.Peru. Ideally 2 weeks before travel.
    • Hepatitis A - Recommended for Argentina.Brazil.Chile.Peru. Ideally 2 weeks before travel.
    • Hepatitis B - Recommended for Argentina.Brazil.Chile.Peru. Ideally 2 months before travel.
    • Rabies - Recommended for Argentina.Chile.Peru. Ideally 1 month before travel.
    • Yellow fever - Recommended for Argentina.Brazil.Peru. Ideally 10 days before travel.
    • Tuberculosis - Recommended for Brazil.Peru. Ideally 3 months before travel.
  • Visa
    • Unfortunately we cannot offer you a visa application service. Whether you need a visa or not depends on your nationality and where you wish to travel. Assuming your home country does not have a visa agreement with the country you're planning to visit, you will need to apply for a visa in advance of your scheduled departure.
    • Here is an indication for which countries you might need a visa. Please contact the local embassy for help applying for visas to these places.
  • Payment information
    • For any tour departing before September 21st, 2026 a full payment is necessary. For tours departing after September 21st, 2026, a minimum payment of $750 is required to confirm your booking with APT. The final payment will be automatically charged to your credit card on the designated due date. The final payment of the remaining balance is required at least 120 days prior to the departure date of your tour. TourRadar never charges you a booking fee and will charge you in the stated currency.
    • The following cards are accepted for "APT" tours: Visa, Maestro, Mastercard, American Express or PayPal. TourRadar does NOT charge you an extra fee for using any of these payment methods.
  • Cancellation Policy
  • Accessibility
    Some tours are not suitable for mobility-restricted traveler, however, some operators may be able to accommodate special requests. For any enquiries, you can contact our customer support team, who are ready and waiting to help you.

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0

Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec