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From
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Best of Italy and Greece with 4-day cruise

14 days
•
From Rome to Oia
4.8 (64 reviews)
  • Woman with a hat standing in front of the Trevi Fountain.
  • Stuffed calamari on a serving tray.
  • The Castel Sant'Angelo with a bridge over a river.
  • Gondolas with an island view in Venice.
    View all

  • Extremely knowledgeable, warm, and attentive. Her professionalism and care made the entire experience smooth and enjoyable.

    Elizabeth•traveled in June5.0
  • Family walking on white and blue buildings stairway.
  • Colorful square with cafes and yellow buildings.
  • View of bridges over the Arno River in Florence.
  • Santorini with blue domes and sea view.
  • The Acropolis complex on a hill in Athens.
    View all
From
$4,370
-3%
US $4,239 per person
+ $205 Mandatory Port Taxes and Cruise Gratuities

Price based on Cheapest Room

Price based on Shared Room

Price based on Private Single Room

Price based on Private Double Room

Select Date

Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
1 Adult2 Adults, 1 Child2 Children

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

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Best price guarantee Learn More

Plan your adventure:
Platinum Operator
Eskapas
City & Culture
Immerse yourself in rich history and local traditions
Group Tour
Join a group and forge lifelong friendships
Partially Guided
Independent travel, featuring selected guided excursions
Low Intensity
Travelers can expect some light physical activities
Guided in English
Other languages on request: Spanish
Group Size 1 - 45
Ages 6+
Image of a map showing the route of the tour

Itinerary

  1. Day 1

    Rome

    Rome
    Start point
    Rome, Italy (Rome airports (FCO or CIA))

    Optional Activities

    • Airport transfer (available for upgrade)
    Itinerary Image 1Itinerary Image 2Itinerary Image 3
  2. Day 2

    Rome

    Rome
    Meals
    Breakfast

    Included Activities

    • Exclusive guided tour of the Colosseum with arena floor access
    • Guided tour of Roman Forum
    • Guided tour of Palatine Hill
    Landmarks
    Colosseum
    Roman Forum
    Palatine Hill
    Itinerary Image 1Itinerary Image 2Itinerary Image 3
  3. Day 3

    Rome - Assisi - Siena - Florence

    Rome - Assisi - Siena - Florence
    Meals
    Breakfast

    Included Activities

    • Visit Basilica of St. Francis in Assisi

    Optional Activities

    • Lunch in Assisi
    Landmarks
    Basilica of St. Francis
    Piazza del Campo
    Itinerary Image 1Itinerary Image 2Itinerary Image 3
  4. Day 4

    Florence

    Florence
    Meals
    Breakfast

    Included Activities

    • Visit Duomo
    • View Brunelleschi's Dome
    • View Giotto's Bell Tower
    • Visit Baptistery
    • Visit Piazza della Signoria
    • Visit Palazzo Vecchio
    • Visit Santa Croce Basilica

    Optional Activities

    • Guided excursion to Uffizi Gallery
    Landmarks
    Duomo of Florence
    Giotto's Bell Tower
    Baptistery of Florence
    Piazza della Signoria
    Palazzo Vecchio
    Santa Croce Basilica
    Uffizi Gallery
    Itinerary Image 1
  5. Day 5

    Florence - Bologna - Venice

    Florence - Bologna - Venice
    Meals
    Breakfast

    Included Activities

    • Walking tour of Bologna from Piazza Malpighi to Piazza Maggiore

    Optional Activities

    • Lunch in Bologna
    • Street food tasting and local cuisine exploration
    Landmarks
    Piazza Malpighi
    Piazza Maggiore
    San Petronio Basilica
    Palazzo del Podestà
    Itinerary Image 1Itinerary Image 2
  6. Day 6

    Venice

    Venice
    Meals
    Breakfast

    Included Activities

    • Transfer to Piazza San Marco
    • Guided tour of Venice highlights
    • Visit Doge's Palace (outside)
    • Cross Bridge of Sighs

    Optional Activities

    • Lunch
    Landmarks
    Piazza San Marco
    Doge's Palace
    Bridge of Sighs
  7. Day 7

    Venice - Tuscany - Montepulciano - Rome

    Venice - Tuscany - Montepulciano - Rome
    Meals
    Breakfast

    Optional Activities

    • Stroll through Montepulciano historic center
    • Lunch in Montepulciano
    Landmarks
    Montepulciano
  8. Day 8

    Rome to Athens

    Rome to Athens
    Meals
    Breakfast

    Included Activities

    • Flight from Rome to Athens
    • Airport transfer to hotel in Athens
    Itinerary Image 1Itinerary Image 2Itinerary Image 3
  9. Day 9

    Athens

    Athens
    Meals
    Breakfast

    Included Activities

    • Visit Panathenaic Stadium
    • Pass by Prime Minister's residence
    • Visit Temple of Olympian Zeus
    • Visit Hadrian's Arch
    • Visit Parliament
    • View memorial to the Unknown Soldier
    • Visit Academy
    • Visit University
    • Visit National Library
    • Visit Constitution Square
    • Guided tour of Acropolis including Propylaea
    • Visit Temple of Athena Nike
    • Visit Erechtheion
    • Visit Parthenon
    • Visit new Acropolis Museum
    Landmarks
    Panathenaic Stadium
    Temple of Olympian Zeus
    Hadrian's Arch
    Parliament of Greece
    Academy of Athens
    National Library of Greece
    Syntagma Square
    Acropolis
    Propylaea
    Temple of Athena Nike
    Erechtheion
    Parthenon
    Acropolis Museum
    Itinerary Image 1Itinerary Image 2
  10. Day 10

    Athens to Mykonos

    Athens to Mykonos
    Meals
    Breakfast, Lunch (Full board on cruise ship), Dinner (Full board on cruise ship)

    Included Activities

    • Cruise embarkation
    • Evening exploration of Mykonos Old Town (Chora)
    Landmarks
    Mykonos Old Town (Chora)
    Mykonos Windmills
    Little Venice
    Itinerary Image 1Itinerary Image 2Itinerary Image 3
  11. Day 11

    Kusadasi - Patmos

    Kusadasi - Patmos
    Meals
    Breakfast, Lunch (Full board on cruise ship), Dinner (Full board on cruise ship)

    Included Activities

    • Full board on cruise ship

    Optional Activities

    • Shore excursion to Ephesus ruins from Kusadasi
    • Visit Monastery of St. John in Patmos
    • Visit Cave of the Apocalypse
    • Exploration of Hora village
    Landmarks
    Ephesus
    Monastery of St. John
    Cave of the Apocalypse
    Itinerary Image 1
  12. Day 12

    Rhodes

    Rhodes
    Meals
    Breakfast, Lunch (Full board on cruise ship), Dinner (Full board on cruise ship)

    Included Activities

    • Full board on cruise ship

    Optional Activities

    • Visit Palace of the Grand Master
    • Explore Old Town and Street of the Knights
    • Relax at Elli Beach
    • Visit ancient site of Lindos with clifftop acropolis
    • Shore excursions
    Landmarks
    Old Town of Rhodes
    Street of the Knights
    Palace of the Grand Master
    Elli Beach
    Lindos Acropolis
    Itinerary Image 1
  13. Day 13

    Heraklion - Santorini

    Heraklion - Santorini
    Meals
    Breakfast, Lunch (Full board on cruise ship), Dinner (Full board on cruise ship)

    Included Activities

    • Full board on cruise ship

    Optional Activities

    • Shore excursion to Palace of Knossos from Heraklion
    • Exploration of Fira
    • Visit to Oia village
    • Cable car ride in Santorini
    • Shore excursions
    Landmarks
    Palace of Knossos
    Fira
    Oia
    Santorini Caldera
    Itinerary Image 1Itinerary Image 2Itinerary Image 3
  14. Day 14

    Athens

    Athens
    End point
    Athens International Airport Eleftherios Venizelos (ATH) Διεθνής Αερολιμένας Αθηνών Ελευθέριος Βενιζέλος, Αττική Οδός, Spata-Loutsa, Attica 190 04, Greece (Athens Airport)
    Meals
    Breakfast

    Included Activities

    • Airport transfer

Want to read it later?

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What's Included

Expand All
  • Accommodation
  • Flights
  • Guide
  • Meals
  • Transport
  • Optional Extras

What's Not Included

  • Insurance
  • Additional Services

Operated by

Eskapas

Platinum Operator
Rating
4.7 (2,459 reviews)
Response time
7 hours
Response rate
100%
Cancellation policy

Traveler Reviews

4.8
Overall rating based on 64 Reviews
  • Itinerary
    4.8
  • Transport
    4.9
  • Guide
    4.9
  • Accommodation
    4.7
  • Food
    4.7
  • Tour Operator
    4.7

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Highest First
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  • Harold3.0•October 2025
    We were so looking forward to our Italy and Greece trip especially since it was our 50th Anniversary trip. We felt...
    Show more
    Traveled in September 2025
    Reply from: Eskapas
    Hi Harold, Thank you for your review. That was unfortunate that your cruise ship had a long maintenance breakdown and your cruise portion is cancelled. The only option in such short time was to offer you a stay over in Santorini. Sorry for the trouble caused by the cruise ship but it was an unexpected incident. We will give you additional 10% discount for your future bookings at Eskapas Travel. Kind Regards, Aysegul
    Show more
  • Elizabeth5.0•June 2025
    Fantasy tour guide - Sabrina was an outstanding tour guide—extremely knowledgeable, warm, and attentive. She had a...
    Show more
    Traveled in May 2025
    Reply from: Eskapas
    Hi Elizabeth, Thank you for your time to review us. Kind regards, Aysegul
    Show more
  • Gabriel5.0•November 2024
    We got to see every place they promised, and nothing felt rushed. They were very meticulous about time management....
    Show more
    Traveled in April 2023
    Review collected by Eskapas
  • Ivy4.8•November 2024
    The tour guides were excellent—informative, organized, caring, fun, and approachable. There was a great balance...
    Show more
    Traveled in August 2024
    Review collected by Eskapas
  • Julian4.2•November 2024
    It wasn’t the best tour I’ve been on, but I still found it above average. There were a few minor issues, and although...
    Show more
    Traveled in October 2023
    Review collected by Eskapas
    Reply from: Eskapas
    Thank you for your time to review us. Kind Regards, Aysegul
    Show more
  • Brooke5.0•November 2024
    The staff were considerate, respectful, and thoughtful throughout the trip. A big thank you to Eskapas for such a...
    Show more
    Traveled in September 2024
    Review collected by Eskapas
    Reply from: Eskapas
    Thank you for your time to review us. Regards, Aysegul
    Show more
  • Patrick4.3•November 2024
    I joined this tour with my granddaughter and daughter, and we didn’t encounter any major issues. Since I enjoy...
    Show more
    Traveled in April 2024
    Review collected by Eskapas
    Reply from: Eskapas
    Thank you for your review. Regards, Aysegul
    Show more
  • Mateo5.0•November 2024
    Italian and Greek cuisine is an absolute paradise for vegetarians. I have to start by saying that! I couldn’t get...
    Show more
    Traveled in September 2024
    Review collected by Eskapas
    Reply from: Eskapas
    Thank you for your time to review us. Regards, Aysegul
    Show more
  • Lucia4.8•November 2024
    It was fun, fast-paced, and friendly. If you're over 65, you might find it a bit tiring, but I definitely think it's...
    Show more
    Traveled in October 2024
    Review collected by Eskapas
  • Diego4.7•November 2024
    The guides were knowledgeable and professional. The trip was great, with so many beautiful places, especially Venice...
    Show more
    Traveled in October 2024
    Review collected by Eskapas

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Dates & Availability

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Select Date

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2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
1 Adult2 Adults, 1 Child2 Children

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0
Upcoming departures
Hurry, deals only available for a limited time!
Ends on 26 Aug, 2026
  • Instant Confirmation
    -3%
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    10 Oct, 2026
    To Friday
    23 Oct, 2026
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    This departure date is available and will 100% depart
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    $4,715
    US$4,574 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
    $205
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    6 Mar, 2027
    To Friday
    19 Mar, 2027
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    US$4,239 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
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  • Instant Confirmation
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    13 Mar, 2027
    To Friday
    26 Mar, 2027
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    This departure date is available and will 100% depart
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    $4,370
    US$4,239 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
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    20 Mar, 2027
    To Friday
    2 Apr, 2027
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    This departure date is available and will 100% depart
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    $4,370
    US$4,239 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
    $205
  • Instant Confirmation
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    27 Mar, 2027
    To Friday
    9 Apr, 2027
    English, Spanish
    This departure date is available and will 100% depart
    Guaranteed departure
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    $4,370
    US$4,239 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
    $205
  • Instant Confirmation
    -3%
    From Saturday
    3 Apr, 2027
    To Friday
    16 Apr, 2027
    English, Spanish
    This departure date is available and will 100% depart
    Guaranteed departure
    From:
    $4,715
    US$4,574 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
    $205
  • Instant Confirmation
    -3%
    From Saturday
    10 Apr, 2027
    To Friday
    23 Apr, 2027
    English, Spanish
    This departure date is available and will 100% depart
    Guaranteed departure
    From:
    $4,715
    US$4,574 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
    $205
  • Instant Confirmation
    -3%
    From Saturday
    17 Apr, 2027
    To Friday
    30 Apr, 2027
    English, Spanish
    This departure date is available and will 100% depart
    Guaranteed departure
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    $4,715
    US$4,574 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
    $205
  • Instant Confirmation
    -3%
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    24 Apr, 2027
    To Friday
    7 May, 2027
    English, Spanish
    This departure date is available and will 100% depart
    Guaranteed departure
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    $4,715
    US$4,574 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
    $205
  • Instant Confirmation
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    From Saturday
    1 May, 2027
    To Friday
    14 May, 2027
    English, Spanish
    This departure date is available and will 100% depart
    Guaranteed departure
    From:
    $4,715
    US$4,574 per person
    Price based on Private Double Room
    Mandatory Port Taxes and Cruise Gratuities
    $205

Want to read it later?

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What our customers ask about this tour

The content in our FAQ section is subject to change.
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Try a different search term or ask a question to this adventure's experts
  • L

    Lorraine

    Asked on May 8th, 2026

    can I get an itinerary based on what I requested and not your already premade tours

    Tour Details
    • L

      Lorraine

      Traveler•Written May 2026

      but your tours are not available then. Do u not offer proper custom tours?

    • EskapasOperator•Written May 2026

      we do not run fully bespoke private itineraries from scratch as our default model. However, depending on the destinations and the experiences you have in mind, we may be able to put together something workable around our existing operations, especially for those dates.

    • L

      Lorraine

      Traveler•Written May 2026

      I would like to visit Italy and Greece in 14 days and cover Rome, Florence, Venice, Athens and Santorini from Nov 6th to 20th, with my trip stating from Athens and ending in Rome. I just need your help in arranging trips within these cities that would include a tour guide for all cities, transport between cities like train tickets and 2 airline tickets from Greece to Italy, tickets to all attractions that are famous and must see. Can u help with that?

    • EskapasOperator•Written May 2026

      Unfortunately we do not dismantle our packages.

      • L
      3 more answers
  • E

    Erica

    Asked on April 16th, 2026

    Does an early morning flight at 06:30 from Athens create an issue for the airport transfer on the 26th?

    Flights / Transfers
    • EskapasOperator•Written April 2026

      The cruise returns to Port Lavrion at 06:00am and the time that you will be outside it will be 07:00am and you will be at the Airport at 07:30am. It seems you will need an additional night in Athens.

    • EskapasOperator•Written April 2026

      Please book a flight after 10:30am to be in the safe side or stay another night.

    • E

      Erica

      Traveler•Written April 2026

      We have booked our flights. We will arrive in Rome on June 11 at 12:55 p.m. So we will need extra nights in the hotel for June 11/12. We are departing Athens on June 27 at 06:35 a.m. We will need one night in Athens with an early departure on the 27th.

      • E
      2 more answers
  • J

    Jenny

    Asked on July 18th, 2025

    Is there an option to add a couple of days Istambul city tour with this package?

    Tour Details
    Travel Support
    • EskapasOperator•Written July 2025

      Yes, we can definitely add an Istanbul city break to your trip, including guided visits, hotel accommodation, and airport transfers. Could you please let me know how many days you'd like to stay in Istanbul? Also, will you be booking your flights on your own, or would you prefer us to assist with that? Just a heads-up—October availability is very limited, so I recommend moving forward quickly to secure your spot.

  • S

    Sally

    Asked on July 13th, 2025

    We want to be in one room. We are open to vacation rental that are completely private or hotels with ample space but all together. We just returned from a trip to Africa. It a little weird in that way. Our 14-year-old… They wanted him in his own room and that was odd for us. Obviously his own bed but… we'd like w1 king size bed for myself, my husband and our to be six-year-old and a smaller bed for the older kiddo is ideal.

    Accommodation
    • EskapasOperator•Written July 2025

      The reason behind the idea of accommodation 2 people in one room (max 3 people in a room) the hotels are built that way during their construction plan. The family rooms are usually in resort hotels. We can accommodate four in a room during Greece part including in the cruise ship and in Athens together. Unfortunately the trip in Italy offers double, single, triple room.

    • S

      Sally

      Traveler•Written July 2025

      We only need a king size bed and a smaller bed so whatever works but we can't separate our family. You know what I mean.

    • S

      Sally

      Traveler•Written July 2025

      We're hoping for June 12th ish -July 3rd ish 2026.

      • S
      S
      2 more answers
  • L

    Lynne

    Asked on April 22nd, 2025

    I am Pescatarian - Does not eat meat but eat Fish

    Meals
    • EskapasOperator•Written April 2025

      Being pescatarian won't be a problem—you'll find plenty of suitable options while traveling in both Greece and Italy. I recommend informing your tour leader in Italy when you meet them, just to ensure everything goes smoothly.

  • M

    Mario

    Asked on January 19th, 2025

    Can I book excursions before I arrive?

    Tour Details
    • EskapasOperator•Written January 2025

      Excursions can be booked upon arrival, but you can also inquire about booking in advance.

  • J

    Jason

    Asked on December 4th, 2024

    What type of accommodation will be provided?

    Accommodation
    • EskapasOperator•Written December 2024

      Your hotel accommodations are generally 4-star facilities with various amenities.

  • L

    Lee

    Asked on August 28th, 2024

    I want to book the 12 day tour of Italy and 3 day cruise of greek islands. I saw somewhere it said vativan. Which is what we want. But dont see it in itinerary. There is a trip to some small town for the day. Can we somehow stay in rome and book the vatican rather than easte a day in something we don't want.

    Tour Details
    Travel Support
    • EskapasOperator•Written August 2024

      We can customize the program for you. On Day 2, instead of visiting the Colosseum, we can arrange a tour of the Vatican for you. Another option would be to arrive in Rome a day earlier. We can arrange pre-tour accommodation and a Vatican tour on that extra day at an additional cost.

    • EskapasOperator•Written August 2024

      Since Day 2 falls on a Sunday, the Vatican will be closed. The best option would be for you to arrive a day earlier, allowing us to arrange the Vatican visit for Saturday.

    • L

      Lee

      Traveler•Written August 2024

      That would be great. Arrive a day or two before the tour starts. Ill check our timing and airfares.

      • L
      2 more answers
  • M

    Morgan

    Asked on July 19th, 2024

    are the hotel beds single person sized or more than 2 people? We were trying to book a TRIPLE room but it did not let us because it says only 2 travelers.

    Accommodation
    • EskapasOperator•Written July 2024

      The system doesn't allow you to book because this trip is sold out until March 2025. We recommend you to book 16-day Italy and Greece Highlights with Island Hopping Tour.

    • M

      Morgan

      Traveler•Written July 2024

      do you have any options for 12 days for September? Italy and Greece only?

      • M
      1 more answer
  • T

    Tina

    Asked on July 5th, 2024

    Can the tour group size be adjusted?

    Group size
    • EskapasOperator•Written July 2024

      The standard group size can be modified based on availability, but popular tours may sell out quickly.

Can’t find the answer to your question?
Reach out to the experts at Eskapas with your enquiry, they usually respond within 7 hours.
From
$4,370
-3%
US $4,239 per person
+ $205 Mandatory Port Taxes and Cruise Gratuities

Price based on Cheapest Room

Price based on Shared Room

Price based on Private Single Room

Price based on Private Double Room

Select Date

Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
1 Adult2 Adults, 1 Child2 Children

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0

Best price guarantee Learn More

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Good to Know

Tour ID: 262171

  • Currencies
    €
    Euro
    Greece and Italy
    $
    US Dollar
  • Plugs & Adapters

    As a traveler from USA, Canada, England, Australia, New Zealand, South Africa you will need an adaptor for types C, F, L.

    Type C
    Greece and Turkey
    Type F
    Greece and Turkey
    Type L
    Italy
  • Vaccines
    • These are only indications, so please visit your doctor before you travel to be 100% sure.
    • Hepatitis A - Recommended for Greece.Turkey. Ideally 2 weeks before travel.
    • Hepatitis B - Recommended for Greece.Turkey. Ideally 2 months before travel.
    • Typhoid - Recommended for Turkey. Ideally 2 weeks before travel.
  • Visa
    • Unfortunately we cannot offer you a visa application service. Whether you need a visa or not depends on your nationality and where you wish to travel. Assuming your home country does not have a visa agreement with the country you're planning to visit, you will need to apply for a visa in advance of your scheduled departure.
    • Here is an indication for which countries you might need a visa. Please contact the local embassy for help applying for visas to these places.
  • Payment information
    • For any tour departing before October 31st, 2026 a full payment is necessary. For tours departing after October 31st, 2026, a minimum payment of 20% is required to confirm your booking with Eskapas. The final payment will be automatically charged to your credit card on the designated due date. The final payment of the remaining balance is required at least 70 days prior to the departure date of your tour. TourRadar never charges you a booking fee and will charge you in the stated currency.
    • Some departure dates and prices may vary and Eskapas will contact you with any discrepancies before your booking is confirmed.
    • The following cards are accepted for "Eskapas" tours: Visa, Maestro, Mastercard, American Express or PayPal. TourRadar does NOT charge you an extra fee for using any of these payment methods.
  • Cancellation Policy
  • Insurance

    Our travel protection from our award-winning partner, XCover, means you and your travel companions can book with peace of mind knowing there’s protection available in case your trip doesn’t go to plan. At checkout you will be able to select between different options in case you or the tour are eligible for insurance. In case no option is available, you are always able to purchase travel insurance outside of TourRadar.

    Checking which travel protection options are available for you…
  • Accessibility
    Some tours are not suitable for mobility-restricted traveler, however, some operators may be able to accommodate special requests. For any enquiries, you can contact our customer support team, who are ready and waiting to help you.
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