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2026

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2027

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2028

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Rome to Palermo Tours

Find adventures that start in Rome and then finish in Palermo. Trips from Rome to Palermo are most popular in September, with the most tours doing this route then.

10 best Rome to Palermo tour packages

  • Highlights of Sicily & Southern Italy Tour
     Highlights of Sicily & Southern Italy - 15 destinations
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    In-depth Cultural

    Highlights of Sicily & Southern Italy

    5.0 (359 traveler reviews)

    "Was well planned and enjoyed every moment of the tour."

    Duration
    14 days
    Destinations
    Rome, Sorrento, Capri, Pompeii, Naples, Bari, Lecce,Alberobello,Matera,Reggio Calabria,Taormina,Agrigento,Palermo+6 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Globus
    10% Off
    From $5,019
    US$4,519per person
    Price based on Private Double Room
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  • Southern Italy and Sicily Tour
     Southern Italy and Sicily - 13 destinations
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    In-depth Cultural

    Southern Italy and Sicily

    4.5 (3 traveler reviews)

    "The tour was great with a selection of great cities. Palermo was the best location!"

    Duration
    10 days
    Destinations
    Rome, Pompeii, Sorrento, Capri, Taormina, Enna, Agrigento,Erice,Mondello,Palermo,Monreale+4 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Trafalgar
    10% Off
    From $3,575
    US$3,218per person
    Price based on Shared Room
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  • Grand Italy & Sicily (Classic) Tour
     Grand Italy & Sicily (Classic) - 29 destinations
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    In-depth Cultural

    Grand Italy & Sicily (Classic)

    Duration
    17 days
    Destinations
    Rome, Vatican City, Pisa, Santa Margherita Ligure,Cinque Terre,Monterosso al Mare,Portofino,Lake Maggiore,Baveno,Isola,Venice,Soave,Padua,Florence,San Gimignano,Pompeii,Sorrento,Mount Vesuvius,Naples,Capri,Amalfi,Matera,Alberobello,Giardini Naxos,Taranto,Messina,Villa San Giovanni,Taormina,Palermo+25 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Insight Vacations
    10% Off
    From $6,875
    US$6,188per person
    Price based on Shared Room
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  • Ultimate Italy (Classic) Tour
     Ultimate Italy (Classic) - 28 destinations
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    Explorer

    Ultimate Italy (Classic)

    5.0 (1 traveler review)

    "Trent's charismatic, dynamic and encyclopedic presentation really enhanced the travel and sights."

    Duration
    22 days
    Destinations
    Rome, Siena, Florence, Lucca, Cinque Terre, Pisa, Como,Lake Como,Milan,Verona,Venice,Treviso,Burano,Bologna,Naples,Pompeii,Capri,Amalfi,Positano,Catania,Taormina,Noto,Syracuse,Vittoria,Cefalu,Palermo+19 more
    Age Range
    Ages 18-35
    Operated in
    English
    Operator
    Contiki
    10% Off
    From $4,495
    US$4,046per person
    +$153 upfront costs
    Price based on Shared Room
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  • Tutta Italia To Sicily by Plane And Aeolian Islands Tour
     Tutta Italia To Sicily by Plane And Aeolian Islands - 31 destinations
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    Explorer

    Tutta Italia To Sicily by Plane And Aeolian Islands

    Duration
    18 days
    Destinations
    Rome, Orvieto, Castiglione del Lago, Siena, Monteriggioni,San Gimignano,Florence,Pisa,Cinque Terre,Genoa,Portofino,Milan,Lake Orta,Orta San Giulio,Lake Maggiore,Stresa,Verona,Venice,Palermo,Castelbuono,Tindari,Milazzo,Vulcano,Lipari,Taormina,Catania,Syracuse,Agrigento,Marsala,Erice+25 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$3,598per person
    Price based on Private Double Room
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  • Tutta Italia With Beautiful Campania and Sicily Tour
     Tutta Italia With Beautiful Campania and Sicily - 31 destinations
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    Explorer

    Tutta Italia With Beautiful Campania and Sicily

    Duration
    17 days
    Destinations
    Rome, Orvieto, Castiglione del Lago, Siena, Monteriggioni,San Gimignano,Florence,Pisa,Cinque Terre,Genoa,Portofino,Milan,Lake Orta,Orta San Giulio,Lake Maggiore,Stresa,Verona,Venice,Padua,San Marino,Gubbio,Perugia,Assisi,Naples,Capri,Sorrento,Salerno,Messina,Taormina,Palermo+25 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$3,220per person
    Price based on Private Double Room
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  • Italian Escape and Sicily (Classic) Tour
     Italian Escape and Sicily (Classic) - 10 destinations
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    Explorer

    Italian Escape and Sicily (Classic)

    5.0 (1 traveler review)

    "The Sicily portion was the best part of the tour. All of our hotels in the cities visited were centrally located."

    Duration
    13 days
    Destinations
    Rome, Naples, Amalfi, Catania, Taormina, Syracuse, Noto,Agrigento,Cefalu,Palermo+3 more
    Age Range
    Ages 18-35
    Regions
    South ItalySicily
    Operated in
    English
    Operator
    Contiki
    10% Off
    From $2,775
    US$2,498per person
    +$153 upfront costs
    Price based on Shared Room
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  • Country Roads of Southern Italy and Sicily (Small Groups) Tour
     Country Roads of Southern Italy and Sicily (Small Groups) - 15 destinations
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    Explorer

    Country Roads of Southern Italy and Sicily (Small Groups)

    Duration
    14 days
    Destinations
    Rome, Trevi, Sorrento, Capri, Pompeii, Alberobello,Mount Vesuvius,Ostuni,Matera,Taormina,Messina,Mount Etna,Syracuse,Agrigento,Palermo+9 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Insight Vacations
    10% Off
    From
    US$6,375per person
    Price based on Shared Room
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  • Rome to Sicily Tour
     Rome to Sicily - 22 destinations
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    Explorer

    Rome to Sicily

    Duration
    23 days
    Destinations
    Rome, Naples, Pompeii, Mount Vesuvius, Sorrento, Minori,Positano,Civita,Tropea,Stromboli,Reggio Calabria,Taormina,Catania,Syracuse,Noto,Ragusa,Agrigento,Marsala,Erice,Palermo+14 more
    Age Range
    Ages 15+
    Country Region
    South Italy
    Operated in
    English
    Operator
    Intrepid Travel
    10% Off
    From
    US$8,265per person
    Price based on Shared Room
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  • Tutta Italia and Sicily with Aeolian Islands Tour
     Tutta Italia and Sicily with Aeolian Islands - 25 destinations
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    Explorer

    Tutta Italia and Sicily with Aeolian Islands

    Duration
    16 days
    Destinations
    Rome, Orvieto, Castiglione del Lago, Siena, Monteriggioni,San Gimignano,Florence,Pisa,Cinque Terre,Genoa,Portofino,Milan,Lake Orta,Orta San Giulio,Stresa,Verona,Venice,Palermo,Castelbuono,Tindari,Milazzo,Vulcano,Lipari,Taormina+19 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$3,223per person
    Price based on Private Double Room
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  • Beautiful of Puglia, Campania and Sicily Tour
     Beautiful of Puglia, Campania and Sicily - 16 destinations
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    Explorer

    Beautiful of Puglia, Campania and Sicily

    Duration
    8 days
    Destinations
    Rome, Bari, Brindisi, Lecce, Gallipoli, Alberobello, Matera,Naples,Capri,Sorrento,Salerno,Messina,Taormina,Giardini Naxos,Palermo+8 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$1,458per person
    Price based on Private Double Room
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  • Beautiful Campania and Sicily Tour
     Beautiful Campania and Sicily - 9 destinations
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    Explorer

    Beautiful Campania and Sicily

    Duration
    5 days
    Destinations
    Rome, Naples, Capri, Sorrento, Salerno, Messina, Taormina,Giardini Naxos,Palermo+2 more
    Age Range
    All Ages Welcome
    Regions
    South ItalyCampaniaSicily+2 more
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$856per person
    Price based on Private Double Room
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  • Grand Italy & Sicily (Small Groups) Tour
     Grand Italy & Sicily (Small Groups) - 29 destinations
    View Map
    In-depth Cultural

    Grand Italy & Sicily (Small Groups)

    Duration
    17 days
    Destinations
    Rome, Vatican City, Pisa, Santa Margherita Ligure,Cinque Terre,Monterosso al Mare,Portofino,Lake Maggiore,Baveno,Isola,Venice,Soave,Padua,Florence,San Gimignano,Pompeii,Sorrento,Mount Vesuvius,Naples,Capri,Amalfi,Matera,Alberobello,Giardini Naxos,Taranto,Messina,Villa San Giovanni,Taormina,Palermo+25 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Insight Vacations
    10% Off
    From
    US$8,250per person
    Price based on Shared Room
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  • Country Roads of Southern Italy and Sicily (Classic) Tour
     Country Roads of Southern Italy and Sicily (Classic) - 14 destinations
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    Explorer

    Country Roads of Southern Italy and Sicily (Classic)

    Duration
    14 days
    Destinations
    Rome, Sorrento, Capri, Pompeii, Alberobello, Mount Vesuvius,Ostuni,Matera,Taormina,Messina,Mount Etna,Syracuse,Agrigento,Palermo+8 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Insight Vacations
    10% Off
    From $5,295
    US$4,766per person
    Price based on Shared Room
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  • Ultimate Italy (Age 27-35) Tour
     Ultimate Italy (Age 27-35) - 29 destinations
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    Explorer

    Ultimate Italy (Age 27-35)

    5.0 (1 traveler review)
    Duration
    22 days
    Destinations
    Rome, Siena, Florence, Santa Croce, Lucca, Cinque Terre,Pisa,Como,Lake Como,Milan,Verona,Venice,Treviso,Burano,Bologna,Naples,Pompeii,Capri,Amalfi,Positano,Catania,Taormina,Noto,Syracuse,Vittoria,Cefalu,Palermo+21 more
    Age Range
    Ages 27-35
    Operated in
    English
    Operator
    Contiki
    14% Off
    From $5,020
    US$4,293per person
    +$153 upfront costs
    Price based on Shared Room
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