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2026

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2027

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2028

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Rome to Palermo Tours

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Have you imagined Rome down to Sicily's capital? See Amalfi cliffs dropping to turquoise water, Pompeii frozen in volcanic moment, and Etna smoking constantly. Naples is a must visit, along with cannoli in Palermo markets that taste unreal. Don’t miss Agrigento Greek temples and ferry crossing to Sicily. Italy's diversity - north meeting Mediterranean south along this route.

10 best Rome to Palermo tour packages

  • Highlights of Sicily & Southern Italy Tour
     Highlights of Sicily & Southern Italy - 15 destinations
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    In-depth Cultural

    Highlights of Sicily & Southern Italy

    5.0 (313 traveler reviews)

    "The tour was fabulous."

    Duration
    14 days
    Destinations
    Rome, Sorrento, Capri, Pompeii, Naples, Bari, Lecce,Alberobello,Matera,Reggio Calabria,Taormina,Agrigento,Palermo+6 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Globus
    3% Off
    From $4,299
    US$4,149per person
    Price based on Private Double Room
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  • Southern Italy and Sicily Tour
     Southern Italy and Sicily - 13 destinations
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    In-depth Cultural

    Southern Italy and Sicily

    4.5 (3 traveler reviews)

    "By far one of the best bus tours out there!"

    Duration
    10 days
    Destinations
    Rome, Pompeii, Sorrento, Capri, Taormina, Enna, Agrigento,Erice,Mondello,Palermo,Monreale+4 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Trafalgar
    10% Off
    From $3,575
    US$3,218per person
    Price based on Private Double Room
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  • Grand Italy & Sicily (Small Groups) Tour
     Grand Italy & Sicily (Small Groups) - 27 destinations
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    In-depth Cultural

    Grand Italy & Sicily (Small Groups)

    Duration
    17 days
    Destinations
    Rome, Vatican City, Pisa, Santa Margherita Ligure,Cinque Terre,Monterosso al Mare,Portofino,Lake Maggiore,Baveno,Isola Bella,Soave,Padua,Venice,Florence,San Gimignano,Pompeii,Sorrento,Capri,Matera,Alberobello,Taormina,Mount Etna,Palermo+19 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Insight Vacations
    10% Off
    From
    US$10,095per person
    Price based on Private Double Room
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  • Tutta Italia With Beautiful Campania and Sicily Tour
     Tutta Italia With Beautiful Campania and Sicily - 31 destinations
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    Explorer

    Tutta Italia With Beautiful Campania and Sicily

    Duration
    17 days
    Destinations
    Rome, Orvieto, Castiglione del Lago, Siena, Monteriggioni,San Gimignano,Florence,Pisa,Cinque Terre,Genoa,Portofino,Milan,Lake Orta,Orta San Giulio,Lake Maggiore,Stresa,Verona,Venice,Padua,San Marino,Gubbio,Perugia,Assisi,Naples,Capri,Sorrento,Salerno,Messina,Taormina,Palermo+25 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$3,245per person
    Price based on Private Double Room
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  • Tutta Italia To Sicily by Plane And Aeolian Islands Tour
     Tutta Italia To Sicily by Plane And Aeolian Islands - 31 destinations
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    Explorer

    Tutta Italia To Sicily by Plane And Aeolian Islands

    Duration
    18 days
    Destinations
    Rome, Orvieto, Castiglione del Lago, Siena, Monteriggioni,San Gimignano,Florence,Pisa,Cinque Terre,Genoa,Portofino,Milan,Lake Orta,Orta San Giulio,Lake Maggiore,Stresa,Verona,Venice,Palermo,Castelbuono,Tindari,Milazzo,Vulcano,Lipari,Taormina,Catania,Syracuse,Agrigento,Marsala,Erice+25 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$3,542per person
    Price based on Private Double Room
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  • Ultimate Italy (Classic) Tour
     Ultimate Italy (Classic) - 28 destinations
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    Explorer

    Ultimate Italy (Classic)

    5.0 (1 traveler review)

    "Trent's charismatic, dynamic and encyclopedic presentation really enhanced the travel and sights."

    Duration
    22 days
    Destinations
    Rome, Siena, Florence, Lucca, Cinque Terre, Pisa, Como,Lake Como,Milan,Verona,Venice,Treviso,Burano,Bologna,Naples,Pompeii,Capri,Amalfi,Positano,Catania,Taormina,Noto,Syracuse,Vittoria,Cefalu,Palermo+19 more
    Age Range
    Ages 18-35
    Operated in
    English
    Operator
    Contiki
    10% Off
    From $4,875
    US$4,388per person
    +$153 upfront costs
    Price based on Private Double Room
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  • Italian Escape and Sicily (Classic) Tour
     Italian Escape and Sicily (Classic) - 10 destinations
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    Explorer

    Italian Escape and Sicily (Classic)

    5.0 (1 traveler review)

    "The Sicily portion was the best part of the tour. All of our hotels in the cities visited were centrally located."

    Duration
    13 days
    Destinations
    Rome, Naples, Amalfi, Catania, Taormina, Syracuse, Noto,Agrigento,Cefalu,Palermo+3 more
    Age Range
    Ages 18-35
    Regions
    South ItalySicily
    Operated in
    English
    Operator
    Contiki
    10% Off
    From
    US$2,627per person
    +$153 upfront costs
    Price based on Private Double Room
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  • Rome to Sicily Tour
     Rome to Sicily - 22 destinations
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    Explorer

    Rome to Sicily

    Duration
    23 days
    Destinations
    Rome, Naples, Pompeii, Mount Vesuvius, Sorrento, Minori,Positano,Civita,Tropea,Stromboli,Reggio Calabria,Taormina,Catania,Syracuse,Noto,Ragusa,Agrigento,Marsala,Erice,Palermo+14 more
    Age Range
    Ages 15+
    Country Region
    South Italy
    Operated in
    English
    Operator
    Intrepid Travel
    10% Off
    From
    US$8,265per person
    Price based on Private Double Room
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  • Grand Italy & Sicily (Classic) Tour
     Grand Italy & Sicily (Classic) - 25 destinations
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    In-depth Cultural

    Grand Italy & Sicily (Classic)

    Duration
    17 days
    Destinations
    Rome, Vatican City, Pisa, Santa Margherita Ligure,Cinque Terre,Monterosso al Mare,Portofino,Lake Maggiore,Baveno,Isola Bella,Padua,Venice,Florence,San Gimignano,Pompeii,Sorrento,Capri,Matera,Alberobello,Taormina,Palermo+17 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Insight Vacations
    10% Off
    From $6,875
    US$6,188per person
    Price based on Private Double Room
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  • Tutta Italia and Sicily with Aeolian Islands Tour
     Tutta Italia and Sicily with Aeolian Islands - 25 destinations
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    Explorer

    Tutta Italia and Sicily with Aeolian Islands

    Duration
    16 days
    Destinations
    Rome, Orvieto, Castiglione del Lago, Siena, Monteriggioni,San Gimignano,Florence,Pisa,Cinque Terre,Genoa,Portofino,Milan,Lake Orta,Orta San Giulio,Stresa,Verona,Venice,Palermo,Castelbuono,Tindari,Milazzo,Vulcano,Lipari,Taormina+19 more
    Age Range
    All Ages Welcome
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$3,280per person
    Price based on Private Double Room
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  • Beautiful of Puglia, Campania and Sicily Tour
     Beautiful of Puglia, Campania and Sicily - 16 destinations
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    Explorer

    Beautiful of Puglia, Campania and Sicily

    Duration
    8 days
    Destinations
    Rome, Bari, Brindisi, Lecce, Gallipoli, Alberobello, Matera,Naples,Capri,Sorrento,Salerno,Messina,Taormina,Giardini Naxos,Palermo+8 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$1,520per person
    Price based on Private Double Room
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  • Beautiful Campania and Sicily Tour
     Beautiful Campania and Sicily - 9 destinations
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    Explorer

    Beautiful Campania and Sicily

    Duration
    5 days
    Destinations
    Rome, Naples, Capri, Sorrento, Salerno, Messina, Taormina,Giardini Naxos,Palermo+2 more
    Age Range
    All Ages Welcome
    Regions
    South ItalyCampaniaSicily+2 more
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$876per person
    Price based on Private Double Room
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  • Sicily and Southern Italy  Ending in Palermo with Rome Tour
     Sicily and Southern Italy Ending in Palermo with Rome - 13 destinations
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    Explorer

    Sicily and Southern Italy Ending in Palermo with Rome

    Duration
    10 days
    Destinations
    Rome, Naples, Capri, Sorrento, Salerno, Paola, Messina,Taormina,Catania,Syracuse,Marsala,Erice,Palermo+6 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Europamundo
    10% Off
    From
    US$1,420per person
    Price based on Private Double Room
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  • Country Roads of Southern Italy and Sicily (Classic) Tour
     Country Roads of Southern Italy and Sicily (Classic) - 15 destinations
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    Explorer

    Country Roads of Southern Italy and Sicily (Classic)

    Duration
    14 days
    Destinations
    Rome, Sorrento, Capri, Pompeii, Alberobello, Ostuni,Polignano a Mare,Matera,Taormina,Mount Etna,Syracuse,Agrigento,Palermo+7 more
    Age Range
    All Ages Welcome
    Country Region
    South Italy
    Operated in
    English
    Operator
    Insight Vacations
    12% Off
    From $5,295
    US$4,660per person
    Price based on Private Double Room
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  • Italian Escape and Sicily (Age 27 To 35) Tour
     Italian Escape and Sicily (Age 27 To 35) - 14 destinations
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    Explorer

    Italian Escape and Sicily (Age 27 To 35)

    5.0 (1 traveler review)
    Duration
    13 days
    Destinations
    Rome, Pompeii, Naples, Capri, Salerno, Positano, Catania,Taormina,Noto,Syracuse,Cefalu,Palermo+5 more
    Age Range
    Ages 27-35
    Country Region
    South Italy
    Operated in
    English
    Operator
    Contiki
    10% Off
    From $3,222
    US$2,900per person
    +$153 upfront costs
    Price based on Private Double Room
    View tour