There's something magical about watching dawn break over Angkor Wat, then spending days drifting through floating villages along the Mekong. Ta Prohm's temples look almost alive with jungle roots, and you'll catch traditional Apsara dancers performing like they've done for centuries. The cruise stops at silk workshops on Silk Island, Phnom Penh's ornate Royal Palace, and those famous Cu Chi Tunnels with their maze-like passages. It’s a true experience.
10 best River cruises from Siem Reap to Ho Chi Minh City
Treasures of the Mekong 2025-2026|2026-2027|2027-2028 - 13 Days
5.0 (1 traveler review)- Duration
- 13 days
- Destinations
- Siem Reap, Banteay Srei, Tonle Sap Lake, Angkor Wat,Kampong Thom,Kampong Cham,Hanchey,Koh Pen,Angkor Ban,Koh Oknha Tei,Phnom Penh,Tan Chau,Chau Doc,Sa Dec,Cai Be,Tan Phong,My Tho,Ho Chi Minh City,Cu Chi+15 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $6,230
- US$6,041per person
Price based on Private Double Room
7-Night Cambodia to Vietnam - Mekong River Cruise & Dolphin Encounter
- Duration
- 8 days
- Destinations
- Siem Reap, Kratie, Kampong Cham, Phnom Penh, My An Hung,Cai Be,Thới Bình,My Tho,Ho Chi Minh City+4 more
- Age Range
- Ages 12+
- Operated in
- English
- Operator
- Lotus Cruises
3% Off- From
- US$2,589per person
Price based on Private Double Room
The Mekong in a different way - Between adventure and must-see sites (port-to-port cruise) (26 destinations)
- Duration
- 9 days
- Destinations
- Siem Reap, Koh Chen, Kampong Chhnang, Kampong Tralach,Oudong,Phnom Penh,Chau Doc,Sa Dec,Cai Be,My Tho,Thoi Son Island,Ho Chi Minh City+8 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
3% Off- From
- US$1,968per person
Price based on Private Double Room
Riches of the Mekong 2026
5.0 (1 traveler review)- Duration
- 8 days
- Destinations
- Siem Reap, Kampong Cham, Angkor Ban, Koh Oknha Tei,Phnom Penh,Oudong,Tan Chau,Mekong Delta,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+8 more
- Age Range
- Ages 12+
- Ship
- AmaDara
- River
- Mekong
- Operated in
- English
- Operator
- AmaWaterways
3% Off- From
- US$3,199per person+$250 upfront costs
Price based on Private Double Room- Booking needs min. 2 travelers
The Mekong in a different way - Between adventure and must-see sites
4.5 (1 traveler review)- Duration
- 11 days
- Destinations
- Siem Reap, Tonle Sap Lake, Angkor Wat, Koh Chen,Kompong Chhnang,Kampong Tralach,Oudong,Phnom Penh,Chau Doc,Sa Dec,Cai Be,My Tho,Thoi Son Island,Mekong Delta,Ho Chi Minh City+11 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
3% Off- From
- US$2,379per person
Price based on Private Double Room
Wonders of Cambodia, Vietnam & the Mekong 2026-2027 - 13 Days
5.0 (1 traveler review)- Duration
- 13 days
- Destinations
- Siem Reap, Angkor Wat, Banteay Srei, Tonle Sap Lake,Kampong Tralach,Oudong,Phnom Penh,Koh Oknha Tei,Tan Chau,Cu Lao Gieng,My An Hung,Sa Dec,Cai Be,Tan Phong,My Tho,Ho Chi Minh City,Cu Chi+13 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Emerald Cruises
3% Off- From $4,720
- US$4,571per person
Price based on Private Double Room
Enchanting Mekong and Siem Reap 2026-2027|2027-2028 - 11 Days (from Siem Reap to Ho Chi Minh City)
- Duration
- 11 days
- Destinations
- Siem Reap, Kampong Tralach, Oudong, Phnom Penh, Tan Chau,Cu Lao Gieng,My An Hung,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+6 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Emerald Cruises
6% Off- From $4,531
- US$4,241per person
Price based on Private Double Room
Luxury Mekong and Temple Discovery Cruise 2025-2026|2026-2027|2027-2028 - 11 Days
- Duration
- 11 days
- Destinations
- Siem Reap, Banteay Srei, Tonle Sap Lake, Angkor Wat,Kampong Thom,Kampong Cham,Hanchey,Koh Pen,Angkor Ban,Koh Oknha Tei,Phnom Penh,Tan Chau,Chau Doc,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+13 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $5,555
- US$5,366per person
Price based on Private Single Room
Fascinating Vietnam, Cambodia & the Mekong River (Southbound) 2027
- Duration
- 13 days
- Destinations
- Siem Reap, Angkor Wat, Banteay Srei, Phnom Penh, Hanchey,Angkor Ban,Kampong Tralach,Chau Doc,Long Khanh,Cu Lao Gieng,Vinh Long,Ho Chi Minh City,Cu Chi+8 more
- Age Range
- Ages 8+
- Ship
- Avalon Saigon
- Operated in
- English
- Operator
- Avalon Waterways
3% Off- From
- US$7,059per person+$175 upfront costs
Price based on Private Double Room
Riches of the Mekong 2027
5.0 (1 traveler review)- Duration
- 8 days
- Destinations
- Siem Reap, Kampong Cham, Angkor Ban, Koh Oknha Tei,Phnom Penh,Oudong,Tan Chau,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+7 more
- Age Range
- Ages 12+
- Ship
- AmaDara
- Operated in
- English
- Operator
- AmaWaterways
3% Off- From
- US$2,899per person+$280 upfront costs
Price based on Private Double Room- Booking needs min. 2 travelers
7-night Mekong Downstream Cambodia Vietnam on Mekong Navigator
4.0 (1 traveler review)"Cabin lovely but situated back of boat and engine noise so loud prevented sleep. Food and service excellent."
- Duration
- 8 days
- Destinations
- Siem Reap, Kampong Cham, Phnom Penh, Cu Lao Gieng,My An Hung,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+5 more
- Age Range
- Ages 12+
- Ship
- Mekong Navigator
- River
- Mekong
- Operated in
- English, German
- Operator
- Lotus Cruises
3% Off- From
- US$3,899per person
Price based on Private Double Room
The Mekong in a different way - Between adventure and must-see sites (port-to-port cruise) (36 destinations)
4.5 (1 traveler review)- Duration
- 11 days
- Destinations
- Siem Reap, Tonle Sap Lake, Angkor Wat, Koh Chen,Kampong Chhnang,Kampong Tralach,Oudong,Phnom Penh,Chau Doc,Sa Dec,Cai Be,My Tho,Thoi Son Island,Mekong Delta,Ho Chi Minh City+11 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
3% Off- From
- US$2,702per person
Price based on Private Double Room
The Mekong in a different way - Between adventure and must-see sites (port-to-port cruise) (24 destinations)
- Duration
- 9 days
- Destinations
- Siem Reap, Koh Chen, Kampong Chhnang, Oudong,Kampong Tralach,Phnom Penh,Vinh Xuong,Chau Doc,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+8 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
3% Off- From
- US$1,754per person
Price based on Private Double Room
Wonders of Cambodia, Vietnam & the Mekong 2026-2027 - 15 Days
5.0 (1 traveler review)- Duration
- 15 days
- Destinations
- Siem Reap, Angkor Ban, Phnom Penh, Tan Chau, My An Hung,Sa Dec,Ho Chi Minh City+2 more
- Age Range
- Ages 12+
- Operated in
- English
- Operator
- Emerald Cruises
3% Off- From $5,120
- US$4,953per person
Price based on Private Double Room
Enchanting Mekong and Siem Reap 2026-2027
- Duration
- 13 days
- Destinations
- Siem Reap, Angkor Wat, Banteay Srei, Tonle Sap Lake,Angkor Ban,Phnom Penh,Koh Oknha Tei,Tan Chau,Cu Lao Gieng,My An Hung,Sa Dec,Ben Tre,My Tho,Ho Chi Minh City+10 more
- Age Range
- Ages 12+
- Operated in
- English
- Operator
- Emerald Cruises
11% Off- From $5,221
- US$4,643per person
Price based on Private Double Room
