What are the key stops and highlights between Siem Reap and Ho Chi Minh City on these river cruises?

Your journey starts near Siem Reap at Angkor Wat and Tonle Sap Lake, then takes you down the Mekong River. In Cambodia, you'll stop at the fishing port of Kampong Chhnang and visit Koh Chen, where local families craft beautiful silverware. The cruise continues to Phnom Penh, where you can explore the Royal Palace and Silver Pagoda. Once in Vietnam, you'll experience the lively floating markets of Chau Doc, wander through Sa Dec's French colonial streets, and watch artisans at work in traditional workshops in Cai Be. As one TourRadar traveler said, "the variety of stops and cultural experiences along the Mekong make this journey truly memorable."

What is the typical duration of a river cruise from Siem Reap to Ho Chi Minh City?

Most cruises last between 8 and 13 days, with many taking 11 or 12 days to complete the journey. For example, if you take the CroisiEurope cruise on the RV Indochine II, you'll spend 11 days visiting places like Angkor Wat, Phnom Penh, and small villages along the Mekong. One TourRadar traveler mentioned, "We had a great time exploring multiple destinations though some activities were repetitive, especially the pagoda visits."

How much does a river cruise from Siem Reap to Ho Chi Minh City typically cost?

You'll find prices starting at USD 2,660 and going up to USD 14,635 per person. If you want a luxury experience with a company like Scenic Luxury Cruises, expect to pay between USD 12,000 and USD 14,000. For a mid-range option, companies like CroisiEurope offer cruises starting around USD 3,900. These prices usually cover your room, food, guided tours, and activities on the ship.

What is the best time of year to take a river cruise from Siem Reap to Ho Chi Minh City?

Most people take these cruises during the dry season from October through February. December and January are especially popular because the weather is nice with less humidity and temperatures between 77-86°F (25-30°C). September and March work too, but you might see some rain. Not many cruises run from June through August because it's hot and wet, with temperatures getting up to 95°F (35°C).

What kind of cultural experiences and activities are included in these river cruises?

You'll get to know local life through village visits, market tours, and temple explorations. In Phnom Penh, you can watch traditional Apsara dancers perform. You'll meet silversmiths in Koh Chen, browse floating markets, and take small boat rides through narrow canals. Many cruises include cooking classes where you'll learn to make Vietnamese dishes, and you'll see how local craftspeople make traditional products. One TourRadar traveler shared, "the combination of cultural shows, local craft demonstrations, and village visits provided an authentic insight into life along the Mekong."

River Cruises from Siem Reap to Ho Chi Minh City

Discover river cruises that depart from Siem Reap and end in Ho Chi Minh City. Cruises from Siem Reap to Ho Chi Minh City are most popular in September, with the most cruises doing this route then.

10 best River cruises from Siem Reap to Ho Chi Minh City

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River Cruise
Enchanting Mekong and Siem Reap 2026 - 11 Days
Duration
11 days
Destinations
Siem Reap, Angkor Wat, Banteay Srei, Kampong Tralach,Oudong,Phnom Penh,Koh Oknha Tei,Tan Chau,My An Hung,Cu Lao Gieng,Sa Dec,Cai Be,Mekong Delta,Tan Phong,My Tho,Ho Chi Minh City+12 more
Age Range
Ages 12+
Operated in
English
Operator
Emerald Cruises
46% Off
From $11,690
US$6,295per person
Price based on Private Double Room
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River Cruise
Essential Vietnam and Cambodia Siem Reap to Ho Chi Minh City (2025)
Duration
12 days
Destinations
Siem Reap, Kampong Cham, Angkor Ban, Phnom Penh,Silk Island,Oudong,Koh Chen,Tan Chau,Sa Dec,Cai Be,My Tho,Cu Chi,Ho Chi Minh City+9 more
Age Range
Ages 8+
Operated in
English
Operator
APT
46% Off
From
US$3,798per person
+$482 upfront costs
Price based on Private Double Room
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River Cruise
Treasures of the Mekong 2025-2026|2026-2027|2027-2028 - 13 Days
5.0 (1 traveler review)
Duration
13 days
Destinations
Siem Reap, Hanchey, Kampong Cham, Angkor Ban, Silk Island,Phnom Penh,Tan Chau,Sa Dec,Cai Be,Ho Chi Minh City+5 more
Age Range
Ages 12+
Ship
Scenic Spirit
River
Mekong
Operated in
English
Operator
Scenic Luxury Cruises & Tours
52% Off
From $13,425
US$6,480per person
Price based on Private Double Room
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River Cruise
Enchanting Mekong and Siem Reap 2026 - 11 Days
Duration
11 days
Destinations
Siem Reap, Kampong Tralach, Oudong, Phnom Penh, Tan Chau,Cu Lao Gieng,My An Hung,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+6 more
Age Range
Ages 12+
Operated in
English
Operator
Emerald Cruises
46% Off
From $11,690
US$6,295per person
Price based on Private Double Room
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River Cruise
7-Night Cambodia to Vietnam - Mekong River Cruise & Dolphin Encounter
Duration
8 days
Destinations
Siem Reap, Kratie, Kampong Cham, Phnom Penh, My An Hung,Cai Be,Thới Bình,My Tho,Ho Chi Minh City+4 more
Age Range
Ages 12+
Operated in
English
Operator
Lotus Cruises
46% Off
From
US$2,589per person
Price based on Private Double Room
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River Cruise
Riches of the Mekong 2026
5.0 (1 traveler review)
Duration
8 days
Destinations
Siem Reap, Kampong Cham, Angkor Ban, Oudong, Phnom Penh,Tan Chau,Sa Dec,My Tho,Ho Chi Minh City+4 more
Age Range
Ages 12+
Ship
AmaDara
River
Mekong
Operated in
English
Operator
AmaWaterways
46% Off
From
US$3,199per person
+$250 upfront costs
Price based on Private Double Room
- Booking needs min. 2 travelers
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River Cruise
Luxury Mekong and Temple Discovery Cruise 2025-2026|2026-2027|2027-2028 - 11 Days
Duration
11 days
Destinations
Siem Reap, Hanchey, Kampong Cham, Angkor Ban, Silk Island,Phnom Penh,Tan Chau,Sa Dec,Cai Be,Ho Chi Minh City+5 more
Age Range
Ages 12+
Ship
Scenic Spirit
River
Mekong
Operated in
English
Operator
Scenic Luxury Cruises & Tours
54% Off
From $12,750
US$5,805per person
Price based on Private Double Room
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River Cruise
The Mekong in a different way - Between adventure and must-seesites (port-to-port cruise) (from Siem Reap to Ho Chi Minh City)
Duration
9 days
Destinations
Siem Reap, Koh Chen, Kampong Tralach, Phnom Penh, Chau Doc,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+4 more
Age Range
All Ages Welcome
River
Mekong
Operated in
English
Operator
CroisiEurope River Cruises
54% Off
From
US$1,969per person
Price based on Private Double Room
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River Cruise
The Mekong in a different way - Between adventure and must-see sites (port-to-port cruise) (10 destinations)
Duration
9 days
Destinations
Siem Reap, Koh Chen, Kampong Chhnang, Kampong Tralach,Phnom Penh,Chau Doc,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+6 more
Age Range
All Ages Welcome
River
Mekong
Operated in
English
Operator
CroisiEurope River Cruises
54% Off
From
US$1,754per person
Price based on Private Double Room
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River Cruise
The Mekong in a different way - Between adventure and must-see sites
4.5 (1 traveler review)
Duration
11 days
Destinations
Siem Reap, Angkor Wat, Koh Chen, Kampong Chhnang,Kampong Tralach,Oudong,Phnom Penh,Chau Doc,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+8 more
Age Range
All Ages Welcome
River
Mekong
Operated in
English
Operator
CroisiEurope River Cruises
54% Off
From
US$2,379per person
Price based on Private Double Room
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River Cruise
From Siem Reap to the Mekong Delta (port-to-port cruise)
4.0 (1 traveler review)
"Comfortable ship. Very nice crew."
ALEKSANDER, traveled in February
Duration
9 days
Destinations
Siem Reap, Tonle Sap Lake, Kampong Tralach, Koh Chen,Phnom Penh,Chau Doc,Sa Dec,Vinh Long,Cai Be,My Tho,Ho Chi Minh City+7 more
Age Range
All Ages Welcome
Ships
RV Indochine RV Indochine II RV Lan Diep+2 ships
River
Mekong
Operated in
English
Operator
CroisiEurope River Cruises
54% Off
From
US$2,304per person
Price based on Private Double Room
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River Cruise
From the Angkor Temples to the Mekong Delta (port-to-port cruise) (22 destinations)
4.5 (1 traveler review)
"Accommodation was very good although our room at the back was a little noisy. Very well organized and excellent tour manager."
Susan, traveled in February
Duration
11 days
Destinations
Siem Reap, Tonle Sap Lake, Kampong Tralach, Koh Chen,Phnom Penh,Chau Doc,Sa Dec,Vinh Long,Cai Be,My Tho,Ho Chi Minh City+7 more
Age Range
All Ages Welcome
Ships
RV Indochine RV Indochine II RV Lan Diep+2 ships
River
Mekong
Operated in
English
Operator
CroisiEurope River Cruises
54% Off
From
US$3,677per person
Price based on Private Double Room
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River Cruise
7-night Mekong Downstream Cambodia Vietnam on Mekong Navigator
4.0 (1 traveler review)
"Cabin lovely but situated back of boat and engine noise so loud prevented sleep. Food and service excellent."
Barbara, traveled in February
Duration
8 days
Destinations
Siem Reap, Kampong Cham, Phnom Penh, Cu Lao Gieng,My An Hung,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+5 more
Age Range
Ages 12+
Ship
Mekong Navigator
River
Mekong
Operated in
English, German
Operator
Lotus Cruises
54% Off
From
US$3,899per person
Price based on Private Double Room
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River Cruise
The Mekong in a different way - Between adventure and must-see sites (port-to-port cruise) (11 destinations)
4.5 (1 traveler review)
Duration
11 days
Destinations
Siem Reap, Koh Chen, Kampong Chhnang, Kampong Tralach,Oudong,Phnom Penh,Chau Doc,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+7 more
Age Range
All Ages Welcome
River
Mekong
Operated in
English
Operator
CroisiEurope River Cruises
54% Off
From
US$2,704per person
Price based on Private Double Room
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River Cruise
Wonders of Cambodia, Vietnam & the Mekong 2026-2027
5.0 (1 traveler review)
Duration
15 days
Destinations
Siem Reap, Angkor Ban, Phnom Penh, Tan Chau, My An Hung,Sa Dec,Ho Chi Minh City+2 more
Age Range
Ages 12+
Operated in
English
Operator
Emerald Cruises
57% Off
From $12,315
US$5,270per person
Price based on Private Double Room
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