River Cruise Tours from Siem Reap to Ho Chi Minh City
There's something magical about watching dawn break over Angkor Wat, then spending days drifting through floating villages along the Mekong. Ta Prohm's temples look almost alive with jungle roots, and you'll catch traditional Apsara dancers performing like they've done for centuries. The cruise stops at silk workshops on Silk Island, Phnom Penh's ornate Royal Palace, and those famous Cu Chi Tunnels with their maze-like passages. It’s a true experience.
10 best River Cruise tours from Siem Reap to Ho Chi Minh City
The Mekong in a different way - Between adventure and must-see sites (port-to-port cruise) (36 destinations)
4.5 (1 traveler review)- Duration
- 11 days
- Destinations
- Siem Reap, Tonle Sap Lake, Angkor Wat, Koh Chen,Kampong Chhnang,Kampong Tralach,Oudong,Phnom Penh,Chau Doc,Sa Dec,Cai Be,My Tho,Thoi Son Island,Mekong Delta,Ho Chi Minh City+11 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
- From
- US$2,627per person
Price based on Private Double RoomSign up and saveDownstream Mekong River Cruise Tours From Cambodia To Vietnam – 10 Days
5.0 (3 traveler reviews)"The scenery was stunning, and we explored vibrant markets and cultural sites along the way."
- Duration
- 10 days
- Destinations
- Siem Reap, Phnom Penh, Chau Doc, Cai Be, Can Tho,Ho Chi Minh City+1 more
- Age Range
- All Ages Welcome
- Regions
- MekongMekong DeltaSouthern Vietnam+1 more
- Operated in
- English
- Operator
- VietLong Travel
- From
- US$1,850per person
Price based on Private Double RoomSign up and saveTreasures of the Mekong 2025-2026|2026-2027 - 13 Days
5.0 (1 traveler review)- Duration
- 13 days
- Destinations
- Siem Reap, Banteay Srei, Tonle Sap Lake, Angkor Wat,Kampong Thom,Kampong Cham,Hanchey,Koh Pen,Angkor Ban,Koh Oknha Tei,Phnom Penh,Tan Chau,Chau Doc,Sa Dec,Cai Be,Tan Phong,My Tho,Ho Chi Minh City,Cu Chi+15 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $6,230
- US$6,041per person
Price based on Private Double RoomSign up and saveRiches of the Mekong 2026
5.0 (1 traveler review)- Duration
- 8 days
- Destinations
- Siem Reap, Kampong Cham, Angkor Ban, Koh Oknha Tei,Phnom Penh,Oudong,Tan Chau,Mekong Delta,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+8 more
- Age Range
- Ages 12+
- Ship
- AmaDara
- River
- Mekong
- Operated in
- English
- Operator
- AmaWaterways
3% Off- From
- US$3,498per person+$250 upfront costs
Price based on Private Double RoomSign up and save- Booking needs min. 2 travelers
The Mekong in a different way - Between adventure and must-see sites (port-to-port cruise) (26 destinations)
- Duration
- 9 days
- Destinations
- Siem Reap, Koh Chen, Kampong Chhnang, Kampong Tralach,Oudong,Phnom Penh,Chau Doc,Sa Dec,Cai Be,My Tho,Thoi Son Island,Ho Chi Minh City+8 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
3% Off- From
- US$1,913per person
Price based on Private Double RoomSign up and saveLuxury Mekong and Temple Discovery Cruise 2026-2027 - 11 Days (from Siem Reap to Ho Chi Minh City)
- Duration
- 11 days
- Destinations
- Siem Reap, Banteay Srei, Tonle Sap Lake, Angkor Wat,Kampong Thom,Kampong Cham,Hanchey,Koh Pen,Angkor Ban,Koh Oknha Tei,Phnom Penh,Tan Chau,Chau Doc,Sa Dec,Tan Phong,Cai Be,Ho Chi Minh City+13 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $5,555
- US$5,366per person
Price based on Private Double RoomSign up and saveWonders of Cambodia, Vietnam & the Mekong 2026-2027
5.0 (1 traveler review)- Duration
- 15 days
- Destinations
- Siem Reap, Angkor Wat, Banteay Srei, Tonle Sap Lake,Angkor Ban,Phnom Penh,Koh Oknha Tei,Tan Chau,Cu Lao Gieng,My An Hung,Sa Dec,Ben Tre,My Tho,Ho Chi Minh City,Cu Chi+11 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Emerald Cruises
6% Off- From $4,870
- US$4,561per person
Price based on Private Double RoomSign up and saveEnchanting Mekong and Siem Reap 2026-2027
- Duration
- 13 days
- Destinations
- Siem Reap, Angkor Wat, Banteay Srei, Tonle Sap Lake,Angkor Ban,Phnom Penh,Koh Oknha Tei,Tan Chau,Cu Lao Gieng,My An Hung,Sa Dec,Ben Tre,My Tho,Ho Chi Minh City+10 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Emerald Cruises
11% Off- From $4,695
- US$4,202per person
Price based on Private Double RoomSign up and save7-night Mekong Downstream Vietnam Cambodia on Mekong Symphony
- Duration
- 8 days
- Destinations
- Siem Reap, Kampong Chhnang, Koh Chen, Kampong Tralach,Phnom Penh,Chau Doc,Sa Dec,Cai Be,Ben Tre,Ho Chi Minh City+6 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Lotus Cruises
11% Off- From
- US$4,099per person
Price based on Private Double RoomSign up and saveRiches of the Mekong 2027
5.0 (1 traveler review)- Duration
- 8 days
- Destinations
- Siem Reap, Kampong Cham, Angkor Ban, Koh Oknha Tei,Phnom Penh,Oudong,Tan Chau,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+7 more
- Age Range
- Ages 12+
- Ship
- AmaDara
- River
- Mekong
- Operated in
- English
- Operator
- AmaWaterways
11% Off- From
- US$3,498per person+$280 upfront costs
Price based on Private Double RoomSign up and save- Booking needs min. 2 travelers
7-night Mekong Downstream Cambodia Vietnam on Mekong Navigator
4.0 (1 traveler review)"Cabin lovely but situated back of boat and engine noise so loud prevented sleep. Food and service excellent."
- Duration
- 8 days
- Destinations
- Siem Reap, Kampong Cham, Phnom Penh, Cu Lao Gieng,My An Hung,Sa Dec,Cai Be,My Tho,Ho Chi Minh City+5 more
- Age Range
- Ages 12+
- Ship
- Mekong Navigator
- River
- Mekong
- Operated in
- English, German
- Operator
- Lotus Cruises
11% Off- From
- US$3,099per person
Price based on Private Double RoomSign up and saveFascinating Vietnam, Cambodia & the Mekong River (Southbound) 2027
- Duration
- 13 days
- Destinations
- Siem Reap, Angkor Wat, Banteay Srei, Phnom Penh, Hanchey,Angkor Ban,Kampong Tralach,Chau Doc,Long Khanh,Cu Lao Gieng,Vinh Long,Ho Chi Minh City,Cu Chi+8 more
- Age Range
- Ages 8+
- Ship
- Avalon Saigon
- River
- Mekong
- Operated in
- English
- Operator
- Avalon Waterways
11% Off- From
- US$7,149per person+$175 upfront costs
Price based on Private Double RoomSign up and saveTemple Discovery and Meandering along the Mekong Cruise (19 destinations)
- Duration
- 13 days
- Destinations
- Siem Reap, Banteay Srei, Tonle Sap Lake, Angkor Wat,Kampong Thom,Kampong Cham,Hanchey,Koh Pen,Angkor Ban,Koh Oknha Tei,Phnom Penh,Tan Chau,Chau Doc,Sa Dec,Cai Be,Tan Phong,Ho Chi Minh City+13 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
27% Off- From $8,980
- US$6,546per person
Price based on Private Double RoomSign up and saveTreasures of the Mekong Meandering Cruise 2026|2027 - 15 Days (from Siem Reap to Ho Chi Minh City)
- Duration
- 15 days
- Destinations
- Siem Reap, Hanchey, Kampong Cham, Angkor Ban, Silk Island,Phnom Penh,Tan Chau,Sa Dec,Cai Be,Ho Chi Minh City+5 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $8,320
- US$8,032per person
Price based on Private Double RoomSign up and saveTreasures of the Mekong 2026-2027 - 13 Days (from Siem Reap to Ho Chi Minh City)
5.0 (1 traveler review)- Duration
- 13 days
- Destinations
- Siem Reap, Banteay Srei, Tonle Sap Lake, Angkor Wat,Kampong Thom,Kampong Cham,Hanchey,Koh Pen,Angkor Ban,Koh Oknha Tei,Phnom Penh,Tan Chau,Chau Doc,Sa Dec,Cai Be,Tan Phong,Ho Chi Minh City,Cu Chi+14 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $6,230
- US$6,041per person
Price based on Private Double RoomSign up and save





























