River Cruises from Ho Chi Minh City to Siem Reap
Think about cruising from the Mekong Delta all the way to Angkor's temples. You'll explore the Reunification Palace, navigate Cu Chi tunnels, sample honey tea at bee farms, and float through twelve incredible destinations across Southeast Asia. This is culture on a different level, teaching you about a new way of life you might otherwise miss.
Quick filters
Quick filters
From the Mekong Delta to Siem Reap
- Duration
- 9 days
- Destinations
- Ho Chi Minh City, Cu Chi, My Tho, Vinh Long, Cai Be, Sa Dec,Chau Doc,Phnom Penh,Koh Chen,Kampong Tralach,Kampong Chhnang,Tonle Sap Lake,Siem Reap+7 more
- Age Range
- All Ages Welcome
- Ships
- RV IndochineRV Indochine II RV Lan Diep+2 ships
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
Sign up to unlock savings- From
- US$2,019per person
Price based on Private Double Room
Luxury Mekong and Temple Discovery Cruise 2026-2027/2027-2028 - 11 Days (from Ho Chi Minh City to Siem Reap)
- Duration
- 11 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Tan Phong, Sa Dec,Tan Chau,Chau Doc,Phnom Penh,Oudong,Silk Island,Angkor Ban,Kampong Cham,Hanchey,Koh Pen,Kampong Thom,Kampong Kdei,Siem Reap,Banteay Srei,Tonle Sap Lake,Angkor Wat+15 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
18% offSign up to unlock savings- From $7,080
- US$5,815per person
Price based on Private Double Room
7-night Mekong Upstream Vietnam Cambodia on Mekong Symphony
- Duration
- 8 days
- Destinations
- Ho Chi Minh City, Cai Be, Sa Dec, Chau Doc, Phnom Penh,Koh Chen,Kampong Tralach,Kampong Chhnang,Siem Reap+4 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Lotus Cruises
18% offSign up to unlock savings- From
- US$5,199per person
Price based on Private Double Room
Charms of the Mekong 2027
- Duration
- 8 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau,Phnom Penh,Oudong,Kampong Tralach,Koh Oknha Tei,Angkor Ban,Kampong Cham,Siem Reap+7 more
- Age Range
- Ages 12+
- Ship
- AmaDara
- River
- Mekong
- Operated in
- English
- Operator
- AmaWaterways
18% offSign up to unlock savings- From
- US$3,299per person+$280 upfront costs
Price based on Private Double Room- Booking needs min. 2 travelers
Charms of the Mekong 2028
- Duration
- 8 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau,Phnom Penh,Oudong,Kampong Tralach,Koh Oknha Tei,Angkor Ban,Kampong Cham,Siem Reap+7 more
- Age Range
- Ages 12+
- Ship
- AmaDara
- River
- Mekong
- Operated in
- English
- Operator
- AmaWaterways
18% offSign up to unlock savings- From
- US$3,199per person+$280 upfront costs
Price based on Private Double Room- Booking needs min. 2 travelers
The Mekong in a different way - Between adventure and must-seesites (port-to-port cruise, 14 destinations)
- Duration
- 9 days
- Destinations
- Ho Chi Minh City, My Tho, Thoi Son Island, Cai Be, Sa Dec,Chau Doc,Vinh Xuong,Phnom Penh,Kampong Tralach,Oudong,Kompong Chhnang,Kampong Cham,Koh Chen,Siem Reap+9 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
18% offSign up to unlock savings- From
- US$1,883per person
Price based on Private Double Room
Meandering along the Mekong and Temple Discovery Cruise
- Duration
- 13 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau,Chau Doc,Phnom Penh,Oudong,Koh Oknha Tei,Angkor Ban,Hanchey,Kampong Cham,Koh Pen,Kampong Thom,Kampong Kdei,Siem Reap,Banteay Srei,Tonle Sap Lake,Angkor Wat+14 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
17% offSign up to unlock savings- From $7,625
- US$6,337per person
Price based on Private Double Room
From the Mekong Delta to the Angkor Temples
- Duration
- 11 days
- Destinations
- Ho Chi Minh City, My Tho, Vinh Long, Sa Dec, Chau Doc,Phnom Penh,Koh Chen,Kampong Tralach,Kampong Chhnang,Tonle Sap Lake,Siem Reap,Angkor Wat+7 more
- Age Range
- All Ages Welcome
- Ships
- RV IndochineRV Indochine II RV Lan Diep+2 ships
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
18% offSign up to unlock savings- From $3,949
- US$3,254per person
Price based on Private Double Room
From the Mekong Delta to Siem Reap (port-to-port cruise)
- Duration
- 9 days
- Destinations
- Ho Chi Minh City, Cu Chi, My Tho, Vinh Long, Cai Be, Sa Dec,Chau Doc,Phnom Penh,Koh Chen,Kampong Tralach,Kampong Chhnang,Tonle Sap Lake,Siem Reap+7 more
- Age Range
- All Ages Welcome
- Ships
- RV IndochineRV Indochine II RV Lan Diep+2 ships
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
18% offSign up to unlock savings- From
- US$2,388per person
Price based on Private Double Room
Treasures of the Mekong Meandering Cruise 2026-2027/2027-2028 - 15 Days (from Ho Chi Minh City to Siem Reap)
- Duration
- 15 days
- Destinations
- Ho Chi Minh City, Cu Chi, My Tho, Cai Be, Tan Phong, Sa Dec,Tan Chau,Chau Doc,Phnom Penh,Oudong,Koh Oknha Tei,Angkor Ban,Hanchey,Kampong Cham,Koh Pen,Kampong Thom,Kampong Kdei,Siem Reap,Banteay Srei,Tonle Sap Lake,Angkor Wat+15 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- River
- Mekong
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
15% offSign up to unlock savings- From $8,320
- US$7,032per person
Price based on Private Double Room
From the Mekong Delta to the Angkor Temples (port-to-port cruise)
"The ship was perfect, the staff friendly and always helpful."
- Duration
- 11 days
- Destinations
- Ho Chi Minh City, Cu Chi, My Tho, Vinh Long, Sa Dec,Chau Doc,Phnom Penh,Koh Chen,Kampong Tralach,Kampong Chhnang,Siem Reap,Tonle Sap Lake,Angkor Wat+8 more
- Age Range
- All Ages Welcome
- Ships
- RV IndochineRV Indochine II RV Lan Diep+2 ships
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
15% offSign up to unlock savings- From
- US$3,740per person
Price based on Private Double Room
7-night Mekong Upstream Vietnam Cambodia on Mekong Navigator
"Great tour with nice food and friendly people."
- Duration
- 8 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Cu Lao Gieng,Phnom Penh,Kampong Cham,Siem Reap+3 more
- Age Range
- Ages 12+
- Ship
- Mekong Navigator
- River
- Mekong
- Operated in
- English, German
- Operator
- Lotus Cruises
15% offSign up to unlock savings- From
- US$3,199per person
Price based on Private Double Room
Upstream Mekong River Cruise Tour From Vietnam To Cambodia – 10 Days
"The journey felt seamless as we transitioned from the busy streets of Vietnam to the peaceful rivers of Cambodia."
- Duration
- 10 days
- Destinations
- Ho Chi Minh City, Cu Chi, Can Tho, Cai Be, Chau Doc,Phnom Penh,Siem Reap+2 more
- Age Range
- All Ages Welcome
- Regions
- MekongSouthern Vietnam+1 more
- Operated in
- English
- Operator
- VietLong Travel
15% offSign up to unlock savings- From
- US$1,850per person
Price based on Private Double Room
Enchanting Mekong and Siem Reap 2026-2027 - 11 Days (from Ho Chi Minh City to Siem Reap)
- Duration
- 11 days
- Destinations
- Ho Chi Minh City, Ben Tre, Sa Dec, My An Hung,Cu Lao Gieng,Tan Chau,Phnom Penh,Oudong,Siem Reap+5 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Emerald Cruises
15% offSign up to unlock savings- From
- US$4,392per person
Price based on Private Double Room
Wonders of Vietnam, Cambodia & the Mekong 2026-2027
- Duration
- 13 days
- Destinations
- Ho Chi Minh City, Cu Chi, Ben Tre, Sa Dec, My An Hung,Cu Lao Gieng,Tan Chau,Phnom Penh,Koh Oknha Tei,Oudong,Siem Reap,Angkor Wat,Banteay Srei,Tonle Sap Lake+9 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Emerald Cruises
28% offSign up to unlock savings- From $4,720
- US$3,421per person
Price based on Private Double Room
