River Cruises from Ho Chi Minh City to Siem Reap
Think about cruising from the Mekong Delta all the way to Angkor's temples. You'll explore the Reunification Palace, navigate Cu Chi tunnels, sample honey tea at bee farms, and float through twelve incredible destinations across Southeast Asia. This is culture on a different level, teaching you about a new way of life you might otherwise miss.
10 best River cruises from Ho Chi Minh City to Siem Reap
Meandering along the Mekong and Temple Discovery Cruise
- Duration
- 13 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Tan Phong, Sa Dec,Tan Chau,Chau Doc,Phnom Penh,Oudong,Koh Oknha Tei,Angkor Ban,Hanchey,Kampong Cham,Koh Pen,Kampong Thom,Siem Reap,Banteay Srei,Tonle Sap Lake,Angkor Wat+14 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
27% Off- From $8,980
- US$6,546per person
Price based on Private Double Room
Treasures of the Mekong 2026-2027 - 13 Days (from Ho Chi Minh City to Siem Reap)
5.0 (1 traveler review)- Duration
- 13 days
- Destinations
- Ho Chi Minh City, Cu Chi, My Tho, Cai Be, Tan Phong, Sa Dec,Tan Chau,Chau Doc,Phnom Penh,Oudong,Koh Oknha Tei,Angkor Ban,Kampong Cham,Hanchey,Koh Pen,Kampong Thom,Siem Reap,Banteay Srei,Tonle Sap Lake,Angkor Wat+14 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $6,230
- US$6,041per person
Price based on Private Double Room
The Mekong in a different way - Between adventure and must-seesites (19 destinations)
4.8 (3 traveler reviews)- Duration
- 11 days
- Destinations
- Ho Chi Minh City, My Tho, Thoi Son Island, Cai Be, Sa Dec,Chau Doc,Vinh Xuong,Phnom Penh,Kampong Tralach,Oudong,Kampong Cham,Kompong Chhnang,Koh Chen,Siem Reap,Angkor Wat,Tonle Sap Lake+11 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
3% Off- From
- US$2,304per person
Price based on Private Double Room
Enchanting Mekong and Siem Reap 2026-2027|2027-2028 - 11 Days (from Ho Chi Minh City to Siem Reap)
- Duration
- 11 days
- Destinations
- Ho Chi Minh City, Ben Tre, Sa Dec, My An Hung,Cu Lao Gieng,Tan Chau,Phnom Penh,Oudong,Siem Reap+5 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Emerald Cruises
4% Off- From $4,370
- US$4,216per person
Price based on Private Double Room
Wonders of Vietnam, Cambodia & the Mekong 2026-2027|2027-2028
- Duration
- 13 days
- Destinations
- Ho Chi Minh City, Cu Chi, Ben Tre, Sa Dec, My An Hung,Cu Lao Gieng,Tan Chau,Phnom Penh,Koh Oknha Tei,Oudong,Siem Reap,Angkor Wat,Banteay Srei,Tonle Sap Lake+9 more
- Age Range
- Ages 12+
- River
- Mekong
- Operated in
- English
- Operator
- Emerald Cruises
3% Off- From $4,720
- US$4,571per person
Price based on Private Double Room
Fascinating Vietnam, Cambodia & the Mekong River (Northbound) 2027
- Duration
- 13 days
- Destinations
- Ho Chi Minh City, Cu Chi, Vinh Long, Cu Lao Gieng,Chau Doc,Phnom Penh,Hanchey,Angkor Ban,Kampong Tralach,Siem Reap,Angkor Wat,Banteay Srei+8 more
- Age Range
- Ages 8+
- Ship
- Avalon Saigon
- Operated in
- English
- Operator
- Avalon Waterways
3% Off- From
- US$7,149per person+$175 upfront costs
Price based on Private Double Room
Charms of the Mekong 2027
- Duration
- 8 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau,Phnom Penh,Oudong,Kampong Tralach,Koh Oknha Tei,Angkor Ban,Kampong Cham,Siem Reap+7 more
- Age Range
- Ages 12+
- Ship
- AmaDara
- Operated in
- English
- Operator
- AmaWaterways
3% Off- From
- US$3,299per person+$280 upfront costs
Price based on Private Double Room- Booking needs min. 2 travelers
Charms of the Mekong 2028
- Duration
- 8 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau,Phnom Penh,Oudong,Kampong Tralach,Koh Oknha Tei,Angkor Ban,Kampong Cham,Siem Reap+7 more
- Age Range
- Ages 12+
- Ship
- AmaDara
- Operated in
- English
- Operator
- AmaWaterways
3% Off- From
- US$3,199per person+$280 upfront costs
Price based on Private Double Room- Booking needs min. 2 travelers
Treasures of the Mekong Meandering Cruise 2026|2027 - 15 Days
- Duration
- 15 days
- Destinations
- Ho Chi Minh City, Cu Chi, My Tho, Cai Be, Tan Phong, Sa Dec,Tan Chau,Chau Doc,Phnom Penh,Oudong,Silk Island,Angkor Ban,Kampong Cham,Hanchey,Siem Reap+9 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $8,130
- US$7,848per person
Price based on Private Double Room
Luxury Mekong and Temple Discovery Cruise 2027-2028|2025-2026|2026-2027 - 11 Days
- Duration
- 11 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Tan Phong, Sa Dec,Tan Chau,Chau Doc,Phnom Penh,Oudong,Koh Oknha Tei,Angkor Ban,Kampong Cham,Hanchey,Koh Pen,Kampong Thom,Siem Reap,Banteay Srei,Tonle Sap Lake,Angkor Wat+14 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $5,555
- US$5,366per person
Price based on Private Double Room
7-night Mekong Upstream Vietnam Cambodia on Mekong Navigator
5.0 (4 traveler reviews)"You must book this tour!!!!"
- Duration
- 8 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Cu Lao Gieng,Phnom Penh,Kampong Cham,Siem Reap+3 more
- Age Range
- Ages 12+
- Ship
- Mekong Navigator
- River
- Mekong
- Operated in
- English, German
- Operator
- Lotus Cruises
3% Off- From
- US$3,199per person
Price based on Private Double Room
The Mekong in a different way - Between adventure and must-seesites (port-to-port cruise) (14 destinations)
- Duration
- 9 days
- Destinations
- Ho Chi Minh City, My Tho, Thoi Son Island, Cai Be, Sa Dec,Chau Doc,Vinh Xuong,Phnom Penh,Kampong Tralach,Oudong,Kompong Chhnang,Kampong Cham,Koh Chen,Siem Reap+9 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
3% Off- From
- US$1,948per person
Price based on Private Double Room
The Mekong in a different way - Between adventure and must-seesites (11 destinations)
- Duration
- 9 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Chau Doc,Phnom Penh,Kampong Tralach,Oudong,Kampong Chhnang,Koh Chen,Siem Reap+6 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
3% Off- From
- US$1,754per person
Price based on Private Double Room
The Mekong in a different way - Between adventure and must-seesites (port-to-port cruise) (17 destinations)
4.8 (3 traveler reviews)- Duration
- 11 days
- Destinations
- Ho Chi Minh City, My Tho, Thoi Son Island, Cai Be, Sa Dec,Chau Doc,Phnom Penh,Kampong Tralach,Oudong,Kompong Chhnang,Kampong Chhnang,Koh Chen,Siem Reap,Angkor Wat,Tonle Sap Lake+10 more
- Age Range
- All Ages Welcome
- River
- Mekong
- Operated in
- English
- Operator
- CroisiEurope River Cruises
3% Off- From
- US$2,675per person
Price based on Private Double Room
Luxury Mekong and Temple Discovery Cruise 2026-2027 - 11 Days (from Ho Chi Minh City to Siem Reap)
- Duration
- 11 days
- Destinations
- Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau,Chau Doc,Phnom Penh,Oudong,Koh Oknha Tei,Angkor Ban,Kampong Cham,Hanchey,Koh Pen,Kampong Thom,Siem Reap,Banteay Srei,Tonle Sap Lake,Angkor Wat+13 more
- Age Range
- Ages 18+
- Ship
- Scenic Spirit
- Operated in
- English
- Operator
- Scenic Luxury Cruises & Tours
3% Off- From $5,555
- US$5,366per person
Price based on Private Double Room
