Fully Guided Tours & Trips in Midwest USA
Select from our extensive range of 10 fully guided tours to enjoy a worry-free experience through Midwest USA with our expert guides leading the way.
10 best fully guided Midwest USA tours
Compiled by
MelissaMidwest USA travel expert at TourRadar
- Mackinac Island (Chicago, IL to Detroit, MI, 2027)
- Mackinac Island featuring the Tulip Time Festival (Chicago, IL to Detroit, MI)
- Mackinac Island & the Great Lakes 8 Days
- America's Heartland St. Louis, Missouri (Alton) to St Paul, Minnesota
- Chicago and Niagara ROT (including Niagara Falls)
- Mackinac Island (Chicago, IL to Southfield, MI, 2026)
- Scenic Great Lakes with Mackinac Island
- Autumn on the Superior Hiking Trail (Women-Only)
- Mackinac Island & the Great Lakes 9 Days
- Chicago and Niagara ROT (including Niagara Falls USA)
Guides take you through the Henry Ford Museum and Greenfield Village where you'll see Thomas Edison's laboratory and Robert Frost's workshop. Get fully guided tours of Alden B. Dow's National Historic Landmark home and Detroit's Prohibition-era sites, then check out Frederik Meijer Gardens and Sculpture Park.
Duration 9 days Destinations Chicago, Grand Rapids, Mackinaw City, Mackinac Island, Bay City, Detroit, Dearborn Age Range All Ages Welcome Operator Collette From $4,199
6% Off- US$3,949
Duration 9 days Destinations Chicago, Holland, Grand Rapids, Mackinac Island, Detroit, Dearborn Age Range All Ages Welcome Operator Collette From $4,599
5% Off- US$4,349
Mackinac Island & the Great Lakes 8 Days
“He knew lots about every place we stop. Very nice time.”
Jim, traveled in August
Your Tour Director leads this luxury motorcoach trip from Detroit to Chicago, stopping at the Henry Ford Museum and Bronner's Christmas Wonderland in Frankenmuth. Take a horse-drawn carriage tour on Mackinac Island to see the Governor's Mansion and Arch Rock, then pick Frederik Meijer Gardens or Gerald R. Ford Museum.
Duration 8 days Destinations Detroit, Dearborn, Frankenmuth, Mackinac Island, Mackinaw City, Charlevoix, Petoskey, Traverse City, Grand Rapids, Chicago Age Range All Ages Welcome Operator Globus From
5% Off- US$4,199
A dedicated Cruise Director oversees daily included shore excursions while local guides illuminate each port's history. Onboard lectures cover regional topics from Mark Twain to Norwegian settlement. Special tours cater to farming and brewery interests.
No departure dates availableDuration 8 days Destinations St. Louis, Hannibal, Burlington, Nauvoo, Fort Madison, Dubuque, Galena, La Crosse, Decorah, Red WingSee all destinations Age Range Ages 18+ Operator Viking Cruises 
Duration 8 days Destinations Chicago, Cleveland, Niagara Falls, Detroit, Saugatuck Age Range All Ages Welcome Operator Europamundo From
5% Off- US$1,982
Mackinac Island (Chicago, IL to Southfield, MI, 2026)
“The hotel accommodations and included meals were very good.”
William, traveled in September
Rated 4.8/5 from 50+ reviews, professional English-speaking guides lead comprehensive Midwest tours. Regional experts share insights at Chicago landmarks, Mackinac Island, and historic Michigan destinations.
Duration 9 days Destinations Chicago, Grand Rapids, Mackinaw City, Mackinac Island, Bay City, Frankenmuth, Southfield, Dearborn Age Range All Ages Welcome Operator Collette From $4,199
6% Off- US$3,949
Your expert Travel Director takes you through Chicago's Cloud Gate and Navy Pier before a private carriage tour on Mackinac Island shows you Arch Rock and Fort Mackinac. You'll get a docent-led visit at Detroit's Tuskegee Airmen National Museum and stay at the Grand Hotel on Mackinac Island.
Duration 9 days Destinations Chicago, Grand Rapids, Charlevoix, Mackinac Island, Frankenmuth, Detroit, Dearborn Age Range All Ages Welcome Operator Trafalgar From
6% Off- US$3,995
Duration 6 days Destinations Duluth, Tofte, Grand Marais Age Range Ages 18+ Operator Adventures in Good Company From
6% Off- US$3,495
Duration 9 days Destinations Chicago, Holland, Grand Rapids, Traverse City, Charlevoix, Petoskey, Mackinaw City, Mackinac Island, Bay City, FrankenmuthSee all destinations Age Range All Ages Welcome Operator Globus From $4,749
3% Off- US$4,599
Duration 8 days Destinations Chicago, Cleveland, Niagara Falls (USA), Windsor, Detroit Age Range All Ages Welcome Operator Europamundo From
3% Off- US$1,982
