Fully Guided Tours & Trips in Midwest USA
Select from our extensive range of 11 fully guided tours to enjoy a worry-free experience through Midwest USA with our expert guides leading the way.
10 best fully guided Midwest USA tours
Compiled by

MelissaMidwest USA travel expert at TourRadar
- Ark Encounter & Creation Museum Trip
- Mackinac Island (Chicago, IL to Southfield, MI) (2026)
- America's Heartland St. Louis, Missouri (Alton) to St Paul, Minnesota
- Mackinac Island featuring the Tulip Time Festival (Chicago, IL to Detroit, MI)
- Mackinac Island & the Great Lakes 8 Days
- Chicago and Niagara ROT
- Scenic Great Lakes with Mackinac Island
- Mackinac Island & the Great Lakes 9 Days
- Mackinac Island (Chicago, IL to Detroit, MI) (2027)
Travel through Ohio Amish Country and stay at the Berlin Grande Hotel with dinner at a local farm. Tour the Ark Encounter in Williamstown—a 510-foot-long recreation of Noah's Ark—and walk through the Creation Museum's animatronic displays and Flood dioramas, with guides showing you the David Warther Museum's ivory pieces.
Duration 5 days Destinations Berlin Age Range Ages 12+ Operator Tours of Distinction From
- US$1,349
Mackinac Island (Chicago, IL to Southfield, MI) (2026)
57 Reviews by TourRadar travelers“Extremely well organized all the way. Highly recommended.”
Gunda, traveled in September
Rated 4.8/5 from 50+ reviews, professional English-speaking guides lead comprehensive Midwest tours. Regional experts share insights at Chicago landmarks, Mackinac Island, and historic Michigan destinations.
No departure dates availableDuration 9 days Destinations Chicago, Grand Rapids, Mackinac Island, Frankenmuth, Dearborn, Southfield Age Range All Ages Welcome Operator Collette A dedicated Cruise Director oversees daily included shore excursions while local guides illuminate each port's history. Onboard lectures cover regional topics from Mark Twain to Norwegian settlement. Special tours cater to farming and brewery interests.
No departure dates availableDuration 8 days Destinations St. Louis, Hannibal, Dubuque, La Crosse, Red Wing, Saint Paul Age Range Ages 18+ Operator Viking Cruises Mackinac Island featuring the Tulip Time Festival (Chicago, IL to Detroit, MI)
57 Reviews by TourRadar travelers
No departure dates availableDuration 9 days Destinations Chicago, Holland, Grand Rapids, Mackinac Island, Detroit, Dearborn Age Range All Ages Welcome Operator Collette Mackinac Island & the Great Lakes 8 Days
114 Reviews by TourRadar travelers“Clean coach. Lot of great places.”
Mary, traveled in September
Your Tour Director leads this luxury motorcoach trip from Detroit to Chicago, stopping at the Henry Ford Museum and Bronner's Christmas Wonderland in Frankenmuth. Take a horse-drawn carriage tour on Mackinac Island to see the Governor's Mansion and Arch Rock, then pick Frederik Meijer Gardens or Gerald R. Ford Museum.
Duration 8 days Destinations Detroit, Dearborn, Frankenmuth, Mackinac Island, Charlevoix, Petoskey, Traverse City, Grand Rapids, Chicago Age Range All Ages Welcome Operator Globus From $4,199
4% Off- US$4,049You save $150
Duration 8 days Destinations Chicago, Cleveland, Niagara Falls, Detroit, Saugatuck Age Range All Ages Welcome Operator Europamundo From
4% Off- US$1,982
Your expert Travel Director takes you through Chicago's Cloud Gate and Navy Pier before a private carriage tour on Mackinac Island shows you Arch Rock and Fort Mackinac. You'll get a docent-led visit at Detroit's Tuskegee Airmen National Museum and stay at the Grand Hotel on Mackinac Island.
Duration 9 days Destinations Chicago, Grand Rapids, Charlevoix, Mackinac Island, Frankenmuth, Detroit Age Range All Ages Welcome Operator Trafalgar From $4,550
10% Off- US$4,095You save $455
Duration 9 days Destinations Chicago, Holland, Grand Rapids, Traverse City, Charlevoix, Petoskey, Mackinac Island, Frankenmuth, Dearborn Age Range All Ages Welcome Operator Globus From $4,599
5% Off- US$4,349You save $250
Guides take you through the Henry Ford Museum and Greenfield Village where you'll see Thomas Edison's laboratory and Robert Frost's workshop. Get fully guided tours of Alden B. Dow's National Historic Landmark home and Detroit's Prohibition-era sites, then check out Frederik Meijer Gardens and Sculpture Park.
Duration 9 days Destinations Chicago, Mackinac Island, Grand Rapids, Detroit, Dearborn Age Range All Ages Welcome Operator Collette From
5% Off- US$4,199



















