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3-Week South America Tour Packages
3-Week South America Tour Packages

3-Week South America Tour Packages

Imagine South America in three week. Try a Machu Picchu trek, Buenos Aires tango, Iguazu Falls, Rio's Christ statue, and visit the Amazon rainforest. Take in Peru, Argentina, Brazil, maybe Chile or Ecuador. Andean peaks to tropical coasts, colonial cities to jungle lodges. Continent's contrasts hit different, with incredible diversity packed in.

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2026

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Insider tips: Recommended 3-week South America tour itineraries

Compiled by

South America travel expert at TourRadar

NinaSouth America travel expert at TourRadar

  • 21 Day South America Itinerary, incl. Rio de Janeiro and Machu Picchu

    A grand 21-day tour spans 12 South American cities, from Copacabana Beach to Machu Picchu. The luxury Titicaca Express train, 5 domestic flights, and visits to Cusco's Q'oricancha Temple await. Premium hotels complement visits to Iguazu Falls, Buenos Aires, and Sacred Valley.

    Map of Highlights of South America - 21 days
    View itinerary
    • Days 1-3

      Rio de Janeiro, Brazil

      Arrive at Galeão Airport before 2 PM to avoid Rio's heavy afternoon traffic. On your first night take a walk along Copacabana Beach's black and white promenade. For the next two days focus on Rio's main attractions early in the day. Get the first cable car to Sugarloaf Mountain at 8 AM for the best city views without crowds. Visit Christ the Redeemer by taking the cog train through Tijuca National Park. Bring a light jacket since mornings at the top can be cooler than you might expect.

      21 Day South America Itinerary, incl. Rio de Janeiro and Machu Picchu
    • Days 4-5

      Iguazu Falls

      Take a 2-hour flight to Foz do Iguaçu. You'll want to see these falls from both the Brazilian and Argentine sides. Start on the Brazilian side for sweeping views then spend a full day exploring the Argentine side's walkways. Bring a waterproof bag to protect your camera from the heavy spray at Devil's Throat. A natural gas train runs to the falls every 30 minutes.

      21 Day South America Itinerary, incl. Rio de Janeiro and Machu Picchu
    • Days 6-7

      Buenos Aires, Argentina

      Fly in during the morning and get settled in Argentina's capital. Visit the colorful La Boca district before 5 PM for safety. You can take your time with dinner since most locals eat after 9 PM. Book your tango shows ahead of time as good venues fill up fast. For evening walks stick to the upscale Recoleta area.

      21 Day South America Itinerary, incl. Rio de Janeiro and Machu Picchu
    • Days 8-12

      Bolivia's Highlights

      Flying to Sucre through Santa Cruz brings your first real altitude change. Take things slow when you arrive. The historic center is easy to walk but you'll need good shoes for the steep cobblestone streets. La Paz sits at 11,942 feet so give yourself a full day to adjust before serious sightseeing. The Witches' Market is interesting but ask before taking photos.

      21 Day South America Itinerary, incl. Rio de Janeiro and Machu Picchu
    • Days 13-14

      Lake Titicaca Region

      It takes about 4 hours to get from La Paz to Copacabana. Bring warm clothes since the lake area can be cold despite strong sun. If you visit Isla del Sol be ready for some challenging high-altitude hiking. The border crossing into Peru usually takes 1-2 hours.

      21 Day South America Itinerary, incl. Rio de Janeiro and Machu Picchu
    • Days 15-19

      Cusco & Machu Picchu, Peru

      Take the luxury train from Puno to Cusco for great Andean views but know that rail strikes can happen. Stay in Cusco's San Blas neighborhood for its charm and good location. For Machu Picchu take the first 5:30 AM bus from Aguas Calientes to see the site before the crowds. Book Huayna Picchu permits months ahead since they only allow 400 people daily.

      21 Day South America Itinerary, incl. Rio de Janeiro and Machu Picchu
    • Days 20-21

      Lima

      Finish your trip in Peru's capital. The Miraflores and Barranco areas are both safe and full of character. Visit the historic center during daylight hours only. Leave time for Lima's amazing restaurants. Top places like Central need lunch reservations weeks in advance.

      21 Day South America Itinerary, incl. Rio de Janeiro and Machu Picchu
    View itinerary
  • Southern Divide

    A cultural immersion from Lima to Santiago spans 21 days. Machu Picchu, Lake Titicaca's Uros islands, and the Atacama Desert's Valley of the Moon captivate visitors. Local guesthouses and the unique Jukil Community Lodge provide authentic experiences.

    Map of Southern Divide
    View itinerary
    • Lima Peru

      357 mi
    • Cusco Peru

      51 mi
    • Rainbow Mountain Peru

      51 mi
    • Cusco Peru

      14 mi
    • Sacred Valley Peru

      13 mi
    • Ollantaytambo Peru

      18 mi
    • Aguas Calientes Peru

      5 mi
    • Show 16 more

    • Machu Picchu Peru

      40 mi
    • Cusco Peru

      51 mi
    • Rainbow Mountain Peru

      51 mi
    • Cusco Peru

      207 mi
    • Puno Peru

      42 mi
    • Lake Titicaca Bolivia

      19 mi
    • Taquile Island Peru

      5 mi
    • Uros Reed Islands Peru

      17 mi
    • Puno Peru

      132 mi
    • La Paz Bolivia

      257 mi
    • Sucre Bolivia

      52 mi
    • Potosi Bolivia

      90 mi
    • Uyuni Bolivia

      54 mi
    • Uyuni Salt Flat Bolivia

      54 mi
    • Uyuni Bolivia

      54 mi
    • Uyuni Salt Flat Bolivia

      142 mi
    • Red Lagoon (Laguna Colorada) Bolivia

      142 mi
    • Uyuni Salt Flat Bolivia

      194 mi
    • San Pedro De Atacama Chile

      5 mi
    • Valle de la Luna Chile

      742 mi
    • Santiago Chile

    • Southern Divide
    • Southern Divide
    • Southern Divide
    • Southern Divide
    View itinerary
  • South America Revealed (Galapagos North And Central Cruise)

    This 21-day trip takes you through Brazil, Argentina, Peru, and Ecuador, hitting major spots from Rio's Copacabana Beach to the Galápagos Islands. See Iguazú Falls from both the Brazilian and Argentinean sides, check out the UNESCO-listed Historic Centre of Lima, and visit the ancient fortress of Machu Picchu. Walk through Cusco's Sacsayhuamán ruins, see Buenos Aires' pink Casa Rosada, and cruise Black Turtle Cove in the Galápagos where you'll spot green sea turtles and white-tipped reef sharks.

    Map of South America Revealed (Galapagos North And Central Cruise)
    View itinerary
    • Rio de Janeiro Brazil

      739 mi
    • Foz Do Iguacu Brazil

      3 mi
    • Puerto Iguazu Argentina

      662 mi
    • Buenos Aires Argentina

      66 mi
    • San Antonio de Areco Argentina

      1,891 mi
    • Lima Peru

      4 mi
    • Miraflores Peru

      4 mi
    • Show 14 more

    • Lima Peru

      357 mi
    • Cusco Peru

      14 mi
    • Sacred Valley Peru

    • Yucay Peru

      5 mi
    • Chinchero Peru

      4 mi
    • Sacred Valley Peru

      13 mi
    • Ollantaytambo Peru

      15 mi
    • Machu Picchu Peru

      40 mi
    • Cusco Peru

      357 mi
    • Lima Peru

      825 mi
    • Quito Ecuador

      816 mi
    • Baltra Island Ecuador

      13 mi
    • Santa Cruz Island Ecuador

      70 mi
    • Genovesa Island Ecuador

      63 mi
    • South Plaza Island Ecuador

      17 mi
    • Santa Fé Island Ecuador

      24 mi
    • Santa Cruz Island Ecuador

      13 mi
    • Baltra Island Ecuador

      816 mi
    • Quito Ecuador

    • South America Revealed (Galapagos North And Central Cruise)
    • South America Revealed (Galapagos North And Central Cruise)
    • South America Revealed (Galapagos North And Central Cruise)
    • South America Revealed (Galapagos North And Central Cruise)
    View itinerary

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0

Select departure month

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2028

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec