City & Culture Tours & Trips in Italy and Spain
The most comprehensive tours blending Spain and Italy run for 13-14 days, taking cultural enthusiasts well beyond tourist hotspots. Early morning access to Granada's Alhambra Palace and cable car rides up to medieval Orvieto give you special perspectives, while hands-on experiences make these journeys distinctive. You'll master pesto-making in Cinque Terre, join local mushroom hunts through the Pyrenees, and experience grape harvests in French wine country. TourRadar customers often mention how these tours balance expert guidance at major sites, like Rome's Colosseum, with genuine local encounters at family wineries across Tuscany and Rioja. For those with tighter schedules, the 9-day Barcelona to Rome route delivers cultural depth through small group market visits and walks through ancient neighborhoods. Train travel between destinations creates natural chances to meet locals and discover those special places that don't make it into standard guidebooks.
- Choose from 33 Italy and Spain tours
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Had a fantastic first experience with Contiki. The tour manager and driver were AMAZING and made the experience so much better. Rémi was incredibly knowledgeable and more than helpful and accommodating. The itinerary was busy but allowed for free time in every location. Accommodations were as expected, with some exceeding expectations. Free time add ons were all definitely worth the money. I have no complaints and will certainly be doing another Contiki in the future!!
Barcelona to Rome Quest (Standard, Summer ( Until Mar '27), Classic)
10 best City & Culture Italy and Spain tour packages
Compiled by

NadineItaly and Spain travel expert at TourRadar
- Icons of Italy & the French Riviera - Cruise & Land Journey
- Enjoy Andalusia, Mediterranean Coast and Classic Italy
- Barcelona to Rome Quest (Standard, Winter ( Until Mar '27), Classic)
- Discover the French and Spanish Rivieras
- Icons of Italy & Mediterranean Rivieras - Cruise & Land Journey
- Discover Cultures of the West Mediterranean
- Highlights of Spain, Morocco & Italy
- Mediterranean Highlights: Sardinia, Ibiza & the Riviera
- Mediterranean Moments: Spain to Italy
- Mediterranean Odyssey with a Taste of Italy - Cruise & Land Journey
Duration 19 days Destinations Italy, Monaco, France, Spain Age Range Ages 18+ Operator Scenic Luxury Cruises & Tours From
- US$26,350
Duration 15 days Destinations Spain, Italy, Vatican City (Holy See) Age Range Ages 18+ Operator Remaz Tours GmbH From
- US$6,282
Duration 16 days Destinations France, Italy, Spain, Gibraltar Age Range Ages 12+ Operator Emerald Cruises From $18,940
17% Off- US$15,712
Duration 18 days Destinations Italy, France, Monaco, Spain Age Range Ages 18+ Operator Scenic Luxury Cruises & Tours From $24,850
9% Off- US$22,678
Duration 11 days Destinations Spain, Morocco, Gibraltar, France, Italy Age Range Ages 12+ Operator Emerald Cruises From $10,545
14% Off- US$9,071
















