4-Week South America Tour Packages
Four weeks in South America is a big goal, but it's a real trip. You'll visit Iguazu Falls, explore Lima's colonial center, hike the ancient ruins of Machu Picchu, cruise the Amazon rainforest, learn about Buenos Aires' tango scene, and see Rio's Christ the Redeemer. Cross Peru, Brazil, and Argentina to see the glaciers in Patagonia and learn about cultures that range from Incan to European.
Insider tips: Recommended 4-week South America tour itineraries
Compiled by

NinaSouth America travel expert at TourRadar
28 Day Antarctica Itinerary, incl. Weddell Sea and South Georgia Island
A grand 28-day polar expedition through South America takes you to Ushuaia, South Georgia Island, and the Antarctic Peninsula. The voyage includes 9 full days among the Weddell Sea's ice shelves, with visits to Brown Bluff and Kinnes Cove. Expert-led excursions offer prime wildlife viewing opportunities.

- Days 1-3
Ushuaia and Drake Passage
- Days 4-6
Journey to South Georgia
- Days 7-8
Sea Days
- Day 9
South Sandwich Islands
- Days 10-12
Heading South
- Days 13-14
New Swabia
- Days 15-23
Deep Weddell Sea
Explore the Filchner, Ronne and Larsen ice shelves. Look for Weddell seals breeding in these remote waters. The incredibly clear water offers visibility up to 150 feet. The ship moves carefully through dense ice fields.
- Day 24
Brown Bluff & Kinnes Cove
Stop at Brown Bluff's volcanic cliffs if possible. Watch Adelie penguin colonies and keep your camera ready for nearby whales.
- Day 25
Elephant Island
Visit Point Wild, where Shackleton's crew waited for rescue. While landing is uncommon due to weather, Zodiac rides offer good views of this historic location.
- Days 26-27
Drake Passage Return
Head back through typically calmer Drake Passage waters. Sort photos and attend final lectures.
- Day 28
Ushuaia
Return to Ushuaia early morning. Book afternoon flights to allow for weather delays.
25 Day South America Itinerary, incl. La Paz and Rio de Janeiro
Rich landscapes unfold over 25 days across 11 destinations from La Paz to Rio. The route encompasses Bolivia's salt flats, Chile's Atacama Desert, Argentina's colonial cities, and Brazil's tropical islands. Guided tours of Iguazu Falls from both countries and traditional estancia stays included.

- Days 1-2
La Paz, Bolivia
Welcome to the world's highest capital city at 3,500m. The fascinating Witches' Market (Mercado de Hechiceria) is a must-see, where local shamans sell traditional remedies and ceremonial items. Pack lots of warm layers since La Paz gets quite cold at night. Take an overnight bus to Uyuni - you'll get blankets and reclining seats for the journey.

- Days 3-5
Salar de Uyuni & Atacama Desert
The otherworldly Salar de Uyuni salt flats start with a visit to the Train Cemetery. Next up is Chile's Atacama Desert, where you'll find the red waters of Laguna Colorada full of flamingos. Expect basic facilities and very cold desert nights. One traveler shared: "The salt flats at sunrise were incredible, but bring warm socks and layers - I wasn't prepared for how cold it would be at dawn."

- Days 6-8
San Pedro de Atacama & Salta
Take time to explore San Pedro's old town square and try an astronomy tour under the clear desert sky. The drive to Salta, Argentina is long but beautiful. They call it "La Linda" (the beautiful) for good reason. You can climb 1,070 steps up Cerro San Bernardo or take the cable car for amazing valley views.

- Days 9-13
Buenos Aires & Uruguay
A quick flight takes you to energetic Buenos Aires. Walk through colorful La Boca and the historic San Telmo market. Take a boat to Uruguay's Colonia del Sacramento, a UNESCO site. Visit Montevideo before staying at a traditional estancia (ranch) for a real gaucho experience. A past guest wrote: "The estancia stay was a highlight - learning to ride horses and sharing meals with the local family gave us real insight into Uruguayan culture."

- Days 14-17
Iguazu Falls
- Days 18-20
Paraty & Ilha Grande
- Days 21-25
Rio de Janeiro
Lima Peru
357 miCusco Peru
10 miPisac Peru
16 miSacred Valley Peru
8 miMoray Peru
3 miMaras Peru
8 miOllantaytambo Peru
18 miShow 23 more
Aguas Calientes Peru
5 miMachu Picchu Peru
36 miPoroy Peru
4 miCusco Peru
Saqsaywaman Peru
Cusco Peru
207 miPuno Peru
66 miCopacabana Bolivia
12 miIsland of the Sun Bolivia
34 miHuatajata Bolivia
41 miLa Paz Bolivia
287 miUyuni Bolivia
68 miTunupa Volcano Bolivia
21 miUyuni Salt Flat Bolivia
21 miTunupa Volcano Bolivia
215 miSan Pedro De Atacama Chile
43 miSalar de Atacama Chile
29 miToconao Chile
25 miValle de la Luna Chile
44 miEl Tatio Chile
786 miSantiago Chile
63 miValparaiso Chile
162 miMendoza Argentina
611 miBuenos Aires Argentina
662 miPuerto Iguazu Argentina
3 miIguazu Falls Argentina
Foz Do Iguacu Brazil
739 miRio de Janeiro Brazil
What people love about 4-week South America tours
- Ultimate South America (With Train To Machu Picchu)
One of the greatest trips I’ve ever been on! Clari is the best trip manager and the itinerary was phenomenal.
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