4-Week South America Tour Packages
Four weeks in South America is a big goal, but it's a real trip. You'll visit Iguazu Falls, explore Lima's colonial center, hike the ancient ruins of Machu Picchu, cruise the Amazon rainforest, learn about Buenos Aires' tango scene, and see Rio's Christ the Redeemer. Cross Peru, Brazil, and Argentina to see the glaciers in Patagonia and learn about cultures that range from Incan to European.
Insider tips: Recommended 4-week South America tour itineraries
Compiled by

NinaSouth America travel expert at TourRadar
28 Day Antarctica Itinerary, incl. Weddell Sea and South Georgia Island
A grand 28-day polar expedition through South America takes you to Ushuaia, South Georgia Island, and the Antarctic Peninsula. The voyage includes 9 full days among the Weddell Sea's ice shelves, with visits to Brown Bluff and Kinnes Cove. Expert-led excursions offer prime wildlife viewing opportunities.

- Days 1-3
Ushuaia and Drake Passage
- Days 4-6
Journey to South Georgia
- Days 7-8
Sea Days
- Day 9
South Sandwich Islands
- Days 10-12
Heading South
- Days 13-14
New Swabia
- Days 15-23
Deep Weddell Sea
Explore the Filchner, Ronne and Larsen ice shelves. Look for Weddell seals breeding in these remote waters. The incredibly clear water offers visibility up to 150 feet. The ship moves carefully through dense ice fields.
- Day 24
Brown Bluff & Kinnes Cove
Stop at Brown Bluff's volcanic cliffs if possible. Watch Adelie penguin colonies and keep your camera ready for nearby whales.
- Day 25
Elephant Island
Visit Point Wild, where Shackleton's crew waited for rescue. While landing is uncommon due to weather, Zodiac rides offer good views of this historic location.
- Days 26-27
Drake Passage Return
Head back through typically calmer Drake Passage waters. Sort photos and attend final lectures.
- Day 28
Ushuaia
Return to Ushuaia early morning. Book afternoon flights to allow for weather delays.
25 Day South America Itinerary, incl. La Paz and Rio de Janeiro
Rich landscapes unfold over 25 days across 11 destinations from La Paz to Rio. The route encompasses Bolivia's salt flats, Chile's Atacama Desert, Argentina's colonial cities, and Brazil's tropical islands. Guided tours of Iguazu Falls from both countries and traditional estancia stays included.

- Days 1-2
La Paz, Bolivia
Welcome to the world's highest capital city at 3,500m. The fascinating Witches' Market (Mercado de Hechiceria) is a must-see, where local shamans sell traditional remedies and ceremonial items. Pack lots of warm layers since La Paz gets quite cold at night. Take an overnight bus to Uyuni - you'll get blankets and reclining seats for the journey.

- Days 3-5
Salar de Uyuni & Atacama Desert
The otherworldly Salar de Uyuni salt flats start with a visit to the Train Cemetery. Next up is Chile's Atacama Desert, where you'll find the red waters of Laguna Colorada full of flamingos. Expect basic facilities and very cold desert nights. One traveler shared: "The salt flats at sunrise were incredible, but bring warm socks and layers - I wasn't prepared for how cold it would be at dawn."

- Days 6-8
San Pedro de Atacama & Salta
Take time to explore San Pedro's old town square and try an astronomy tour under the clear desert sky. The drive to Salta, Argentina is long but beautiful. They call it "La Linda" (the beautiful) for good reason. You can climb 1,070 steps up Cerro San Bernardo or take the cable car for amazing valley views.

- Days 9-13
Buenos Aires & Uruguay
A quick flight takes you to energetic Buenos Aires. Walk through colorful La Boca and the historic San Telmo market. Take a boat to Uruguay's Colonia del Sacramento, a UNESCO site. Visit Montevideo before staying at a traditional estancia (ranch) for a real gaucho experience. A past guest wrote: "The estancia stay was a highlight - learning to ride horses and sharing meals with the local family gave us real insight into Uruguayan culture."

- Days 14-17
Iguazu Falls
- Days 18-20
Paraty & Ilha Grande
- Days 21-25
Rio de Janeiro
Ultimate Brazil, Patagonia & the Chilean Fjords
This 28-day route through Brazil, Uruguay, Argentina, and Chile takes you to Rio's Sugarloaf Mountain, colonial São Francisco do Sul, and Punta del Este's 'La Mano' sculpture. You'll see World Heritage Punta Piramides, cruise the 64-kilometer Cockburn Channel past glaciers, and reach Cape Horn where the Atlantic meets Pacific.

Rio de Janeiro Brazil
85 miBuzios Brazil
148 miVila do Abraao Brazil
35 miParaty Brazil
58 miIlhabela Brazil
264 miSão Francisco do Sul Brazil
707 miPunta Del Este Uruguay
70 miShow 6 more
Montevideo Uruguay
126 miBuenos Aires Argentina
126 miMontevideo Uruguay
686 miPuerto Piramides Argentina
792 miPunta Arenas Chile
21 miMagdalena Island Chile
126 miAlberto de Agostini National Park Chile
72 miBeagle Channel Chile
91 miHornos Island Chile
91 miUshuaia Argentina
1,474 miBuenos Aires Argentina
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