2-Week Panama Tour Packages
Think two weeks in Panama is too long for a small country? Actually it works perfectly. Panama City deserves several days to visit Casco Viejo, Panama Canal, and the modern skyline. Visit San Blas Islands for Caribbean paradise with Guna culture, and Bocas del Toro on the other Caribbean side. Highland towns like Boquete for coffee and cooler weather, maybe Panama's Pacific beaches, Darién region if you're adventurous.
Insider tips: Recommended 2-week Panama tour itineraries
Compiled by

SteffPanama travel expert at TourRadar
12 Day Panama Itinerary, incl. Panama City and Bocas del Toro
The 12-day Panamanian adventure showcases Panama City's Miraflores Locks, Bocas del Toro's marine paradise, Boquete's cloud forests, and Santa Catalina's UNESCO-listed Coiba Island. Guests enjoy 11 breakfasts, 7 lunches, and 4-star accommodations throughout.

- Days 1-3
Panama City Region:
Start in Panama City. Spend your first evening in Costa del Este, an upscale area good for orientation. Stay in the Financial District for security and convenience. Visit Casco Viejo early on day 2 before the streets heat up. Check online schedules to time your Miraflores Locks visit with ship transits. On day 3, be ready for a 6:30 AM check-in at Flamenco Marina for your canal cruise. Bring extra snacks even though meals are included. The 6-hour journey can feel long.

- Days 4-6
Bocas del Toro:
Fly to Bocas del Toro (1 hour). Weather here is unpredictable so have backup plans ready. Visit Dolphin Bay in early morning when the water is calm. Use reef-safe sunscreen at Coral Cay to protect marine life. Boat trips to Ngobe communities take 30 minutes. If you get seasick easily bring medicine. The drive to Boquete takes 3.5 hours. Sit up front if you don't like winding roads.

- Days 7-8
Boquete Region:
The Cloud Forest zip-line stretches 3 km across 12 cables. You'll need closed-toe shoes and a light jacket for the cooler elevation. Visit coffee plantations between December and March during harvest season. The drive to Santa Catalina takes 4 hours on mountain roads. Download your maps since cell service is limited.

- Days 9-10
Santa Catalina:
- Days 11-12
Return to Panama City:
13 Days in Panama, incl. Panama City and Bocas del Toro
A 13-day adventure winds through 6 unique destinations, from Panama City's modern skyline to Bocas del Toro's Caribbean charm. Visit Boquete's cloud forests, El Valle's volcanic crater, historic Natá de los Caballeros, and traditional villages like Oria Arriba.

- Days 1-3
Panama City
Start in the capital with a morning arrival to dodge peak traffic from Tocumen Airport (45-60 minutes to city center). Take two full days to explore the city. Visit Miraflores Locks around 9 AM to catch the first ships passing through the Panama Canal. Walk through historic Casco Antiguo in early morning or late afternoon when the heat is less intense.

- Day 4
El Valle de Antón
Take a 2.5-hour drive from Panama City to this town set in the world's largest inhabited volcanic crater. The 600m elevation offers a nice break from coastal heat. Visit the butterfly sanctuary in the morning when butterflies are most active. Bring good walking shoes for the El Macho waterfall trail. The path gets slippery after rain.

- Days 5-6
Las Tablas Region
- Days 7-8
Boquete
- Days 9-11
Bocas del Toro
- Days 12-13
Panama City
Harpy and Quetzal in Focus
A remarkable 13-day tour features 4 major destinations: UNESCO-listed Panama City, Soberania National Park's Pipeline Road, Boquete's cloud forests, and Volcán Barú's summit. Wildlife encounters include harpy eagle tracking in Chagres National Park and stays with Embera Indians.

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