3-Week Greece and Italy Tour Packages

What if you explored Imperial Forums in Rome, visited St. Peter's Basilica in Vatican, then toured ancient Meteora monasteries? Discover historic Athens center, stroll through Valley of the Temples. From Roman ruins through Greek islands to Sicilian archaeology, three weeks traces Western civilization's foundations—democracy invented in Athens, empire built from Rome, philosophy debated in both, all visible in standing monuments rather than just textbooks.

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Insider tips: Recommended 3-week Greece And Italy tour itineraries

Compiled by

NadineGreece and Italy travel expert at TourRadar

16 Day Italy & Greece Itinerary, incl. Venice and Athens
Travel 16 days across 24 destinations in Italy and Greece. Walk through Florence's Piazza Santa Croce and Giotto's Gothic Bell Tower, visit Mycenae's archaeological site built in 1350 BC, and see Delphi at the foot of Mt. Parnassus. A 3-night Aegean cruise takes you to Mykonos, Heraklion, and Santorini, with included excursions to Knossos and photo stops at the Corinth Canal built between 1881 and 1893.
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- Days 1-3
  Venice & Verona
  Visit Venice before 9 AM when gondola traffic is light. Get to St. Mark's Square early before cruise ships arrive. Take vaporetto line 1 for excellent canal views at a better price than private gondolas. Visit Juliet's House in Verona during early morning or just before closing to avoid crowds. Plan for a 3.5-hour drive to Montecatini on winding roads. Consider motion sickness medication if needed.
- Days 4-6
  Florence & Rome
  Stay in Montecatini and take regular 45-minute trains to Florence. Book Uffizi tickets online at least one day ahead and arrive 30 minutes before your time slot. For Rome, visit the Colosseum at opening time (8:30 AM) or after 3 PM when crowds decrease. Book early morning Vatican tickets with skip-the-line access.
- Days 7-8
  Athens & Mycenae
  After your 2-hour flight from Rome to Athens, go straight to the Acropolis. Late afternoon has fewer visitors. The next day takes you to Mycenae, about 2 hours by car. The ancient stones require good footwear. A recent visitor noted: "The Lion Gate at Mycenae was incredible but those stones are slippery - wear good grip shoes and take it slow."
- Days 9-11
  Classical Greece Circuit
  Drive 2.5 hours from Mycenae to Olympia through mountain landscapes. Visit the ancient stadium in the morning before it gets hot. The 4-hour drive to Delphi should get you there by 3 PM to see the ruins in pleasant afternoon light. Spend your final day back in Athens exploring the Plaka neighborhood and local tavernas.
- Days 12-16
  Greek Islands Cruise
  Your 3-night cruise stops at Mykonos, Kusadasi (Turkey), Patmos, Heraklion (Crete) and Santorini. Reserve Santorini excursions early. Get to Oia's castle ruins 30 minutes before sunset for the best views. Pack motion sickness medication as afternoon waters can be rough.
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4th RALLY EUROPE 2026
This 21-day trip covers 14 spots across Italy, Greece, and Turkey with stays in Naples, Sorrento, Bari, Athens, Mykonos, Santorini, and Istanbul. Get guided tours of the Acropolis, UNESCO-listed Pompeii, Ephesus's Library of Celsus, and Pamukkale's thermal terraces.
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- Naples Italy
  13 mi
- Pompeii Italy
  10 mi
- Sorrento Italy
  134 mi
- Bari Italy
  65 mi
- Brindisi Italy
  261 mi
- Patras Greece
  109 mi
- Athens Greece
  95 mi
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- Mykonos Greece
  73 mi
- Santorini Greece
  97 mi
- Kos Greece
  71 mi
- Kusadasi Turkey
  8 mi
- Ephesus Archaeological Museum Turkey
  95 mi
- Pamukkale Turkey
  213 mi
- Istanbul Turkey
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Italy and Greece Highlights with Island Hopping
A 16-day Mediterranean adventure connects Vatican Museums, Florence's Duomo, and Athens' Acropolis. Guests stay in premium hotels like Hotel Raffaello and El Greco, enjoying wine tasting in Montepulciano and visits to Mykonos and Santorini.
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- Rome Italy
  81 mi
- Assisi Italy
  67 mi
- Siena Italy
  31 mi
- Florence Italy
  49 mi
- Bologna Italy
  81 mi
- Mestre Italy
  4 mi
- Venice Italy
  4 mi
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- Mestre Italy
  167 mi
- Montepulciano Italy
  90 mi
- Rome Italy
  2 mi
- Vatican City Vatican City (Holy See)
  2 mi
- Rome Italy
  652 mi
- Athens Greece
  75 mi
- Delphi Greece
  96 mi
- Kalabaka Greece
  153 mi
- Metéora Greece
  77 mi
- Thermopylae Greece
  85 mi
- Athens Greece
  95 mi
- Mykonos Greece
  73 mi
- Santorini Greece
  6 mi
- Oia Greece
  139 mi
- Athens Greece
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Greece and Italy 21 Day Tour Packages You'll Love

What people love about 3-week Greece and Italy tours

SonyTraveled in September
4
It was so cultural in history and old cities, the guides were very good, kind and also the workers in the hotel was helpful and very friendly. Ismail Thanks a lot.
Italy and Greece Highlights with Island Hopping
EmmaTraveled in October
4
Positives: Overall the tour was planned very well, it was nice to have all the accomodations and (most) travel items looked after, along with a couple activites. This was a great way to travel being our first time overseas, to have most of this looked after. Negatives: We were supposed to receive our travel documents approx. 14 days prior to departure, but we did not receive them until 7 days before... This was frusterating as we were getting anxious for the trip and wanted more information to review ahead of time. We had to pay city tax at each hotel we were at, this ranged from 4 to 6 euros per person per night, so it added up quickly. This was frusterating as it said all the accomodations were included, and there was no note of this being an additional fee in the ad... All of the transfers were included for Greece, but not for Italy. Luckily I saw this noted in another review before we left, so we were aware. Looking back at the ad it does note all the transfers, but when you don't know where you are going you assume everything is included, it didn't clearly note what wasn't included (ie taxis from train / hotel / last airport, although some were walking distance so wondered if maybe this is why they weren't included)... General comments: It would have been nice if there were a couple more activites included, to have at least 1 in each city if we were there for 2 nights or more (even just a walking tour). We added a vatican city tour in Rome (through TourRadar) which included the museum and sistene chapel which in hindsight we could have just gone to vatican city and walked around / went into St. Peters Basilica as it's free. We booked a pasta making class in Florence (on our own) which was fun and educational. We also booked a boat tour in Venice (on our own) that went to Murano, Torcello and Burano small islands which was nice. I would highly recommend both!
The Highlights of Greece & Italy - 15 Days (Self-guided)