BEST SELECTION & PRICESBEST SELECTIONBEST PRICESTRUSTED PAYMENTS
Sort: Popularity
Filters

Mexico City to Panama City Tours

9 Mexico City to Panama City trips

Find tours that start in Mexico City, and then finish in Panama City in Panama. Trips from Mexico City to Panama City are most popular in January, with the most tours doing this route then.

Save up to 70% - Get early access
starts in 20:59:30

9 Mexico City to Panama City trips

Sort by
  • Sort by
  • Grand Mexico & Panama

    49 day adventure tour through Mexico City, Puebla, Oaxaca and 22 other destinations in 7 different countries

    destinations
    26 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 65 year olds
    accommodation
    Hotel, Berth / Cabin, Sleeper Bus
    transport
    Boat, Local Transport, Private Vehicle, Plane
    operator
    Tucan Travel
    -17%
    Days
    49
    Our saving
    $1,031
    From
    $6,019
    US $ 4,988
    days
    49
    $102 per day
    14 Jan 2018 3 spaces left
    25 Feb 2018 4 spaces left
    View MoreGetDownload Brochure
  • Complete Central America

    65 day discovery tour through Mexico City, Puebla, Oaxaca and 53 other destinations in 9 different countries

    destinations
    66 destinations in 9 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    15 to 70 year olds
    accommodation
    Hotel, Home-stay, Camping, Guesthouse, Sleeper Bus
    transport
    Coach / Bus, Boat, Local Transport, Private Vehicle, Ferry
    operator
    Intrepid Travel
    -15%
    Days
    65
    Our saving
    $940
    From
    $6,270
    US $ 5,330
    days
    65
    $82 per day
    20 Jan 2018 3 spaces left
    3 Feb 2018 2 spaces left
    View MoreGetDownload Brochure
  • Pan American between Mexico City and Panama City (from Panama City to Mexico City)

    55 day discovery tour through Mexico City, Oaxaca, Monte Alban and 35 other destinations in 8 different countries

    destinations
    40 destinations in 8 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    accommodation
    Hotel, Camping
    transport
    Overland Truck, Boat, Plane
    operator
    Dragoman
    Days
    55
    Our saving
    $118
    From
    US $ 4,587
    • +$1,490 local payments
    days
    55
    $83 per day
    9 Apr 2019 10+ spaces left
    View MoreGetDownload Brochure
  • Vida Loca Ways (from Mexico City)

    49 day hop on/off tour through Mexico City, Teotihuacan, Oaxaca and 35 other destinations in 7 different countries

    destinations
    46 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    operator
    Bamba Experience
    Days
    49
    Our saving
    $71
    From
    US $ 2,778
    days
    49
    $57 per day
    26 Nov 2017 10 spaces left
    27 Nov 2017 10 spaces left
    View MoreGetDownload Brochure
  • Zorro Ways (from Mexico City)

    39 day hop on/off tour through Mexico City, Teotihuacan, Oaxaca and 23 other destinations in 6 different countries

    destinations
    33 destinations in 6 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    accommodation
    Home-stay
    operator
    Bamba Experience
    Days
    39
    Our saving
    $55
    From
    US $ 2,144
    days
    39
    $55 per day
    26 Nov 2017 10 spaces left
    27 Nov 2017 10 spaces left
    View MoreGetDownload Brochure
  • Ultimate Central America

    58 day in-depth cultural tour through Mexico City, Teotihuacan, Puebla and 29 other destinations in 7 different countries

    destinations
    34 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    15 to 70 year olds
    accommodation
    Hotel, Home-stay, Camping, Sleeper Bus
    transport
    Coach / Bus, Boat, Mini-coach
    operator
    Intrepid Travel
    -15%
    Days
    58
    Our saving
    $778
    From
    $5,190
    US $ 4,412
    days
    58
    $76 per day
    30 Dec 2017 1 space left
    6 Jan 2018 1 space left
    View MoreGetDownload Brochure
  • Guacamole Ways (from Mexico City)

    47 day discovery tour through Mexico City, Teotihuacan, Oaxaca and 34 other destinations in 7 different countries

    destinations
    44 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    operator
    Bamba Experience
    Days
    47
    Our saving
    $74
    From
    US $ 2,875
    days
    47
    $61 per day
    26 Nov 2017 10 spaces left
    27 Nov 2017 10 spaces left
    View MoreGetDownload Brochure
  • Sofia Ways (from Mexico City)

    38 day hop on/off tour through Mexico City, Teotihuacan, Oaxaca and 22 other destinations in 6 different countries

    destinations
    30 destinations in 6 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    accommodation
    Home-stay
    operator
    Bamba Experience
    Days
    38
    Our saving
    $58
    From
    US $ 2,251
    days
    38
    $59 per day
    26 Nov 2017 10 spaces left
    27 Nov 2017 10 spaces left
    View MoreGetDownload Brochure
  • Limonada Ways (from Mexico City)

    39 day hop on/off tour through Mexico City, Teotihuacan, Oaxaca and 25 other destinations in 7 different countries

    destinations
    34 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    operator
    Bamba Experience
    Days
    39
    Our saving
    $59
    From
    US $ 2,315
    days
    39
    $59 per day
    26 Nov 2017 10 spaces left
    27 Nov 2017 10 spaces left
    View MoreGetDownload Brochure