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Mexico City to Panama City Tours

9 Mexico City to Panama City trips

Find tours that start in Mexico City, and then finish in Panama City in Panama. Trips from Mexico City to Panama City are most popular in April, with the most tours doing this route then.

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9 Mexico City to Panama City trips

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  • Grand Mexico & Panama

    49 day adventure tour through Mexico City, Puebla, Oaxaca and 22 other destinations in 7 different countries

    destinations
    26 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 65 year olds
    accommodation
    Hotel, Berth / Cabin, Sleeper Bus
    transport
    Boat, Local Transport, Private Vehicle, Plane
    operator
    Tucan Travel
    -10%
    Days
    49
    Our saving
    $587
    From
    $6,019
    US $ 5,432
    days
    49
    $111 per day
    14 Jan 2018 4 spaces left
    25 Feb 2018 7 spaces left
    View MoreGetDownload Brochure
  • Complete Central America

    65 day discovery tour through Mexico City, Puebla, Oaxaca and 53 other destinations in 9 different countries

    destinations
    66 destinations in 9 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    15 to 70 year olds
    accommodation
    Hotel, Home-stay, Camping, Guesthouse, Sleeper Bus
    transport
    Coach / Bus, Boat, Local Transport, Private Vehicle, Ferry
    operator
    Intrepid Travel
    -10%
    Days
    65
    Our saving
    $711
    From
    $7,110
    US $ 6,399
    days
    65
    $98 per day
    20 Jan 2018 7 spaces left
    3 Feb 2018 8 spaces left
    View MoreGetDownload Brochure
  • Pan American between Mexico City and Panama City (from Panama City to Mexico City)

    55 day discovery tour through Mexico City, Oaxaca, Monte Alban and 35 other destinations in 8 different countries

    destinations
    40 destinations in 8 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    operator
    Dragoman
    Days
    55
    Our saving
    $183
    From
    US $ 3,485
    • +$1,480 local payments
    days
    55
    $63 per day
    6 Apr 2018 4 spaces left
    9 Apr 2019 10+ spaces left
    View MoreGetDownload Brochure
  • Vida Loca Ways (from Mexico City)

    49 day hop on/off tour through Mexico City, Teotihuacan, Oaxaca and 35 other destinations in 7 different countries

    destinations
    46 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    operator
    Bamba Experience
    Days
    49
    Our saving
    $142
    From
    US $ 2,702
    days
    49
    $55 per day
    27 Sep 2017 10 spaces left
    28 Sep 2017 10 spaces left
    View MoreGetDownload Brochure
  • Zorro Ways (from Mexico City)

    39 day hop on/off tour through Mexico City, Teotihuacan, Oaxaca and 23 other destinations in 6 different countries

    destinations
    33 destinations in 6 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    accommodation
    Home-stay
    operator
    Bamba Experience
    Days
    39
    Our saving
    $110
    From
    US $ 2,089
    days
    39
    $54 per day
    27 Sep 2017 10 spaces left
    28 Sep 2017 10 spaces left
    View MoreGetDownload Brochure
  • Ultimate Central America

    58 day in-depth cultural tour through Mexico City, Teotihuacan, Puebla and 29 other destinations in 7 different countries

    destinations
    34 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    15 to 70 year olds
    accommodation
    Hotel, Home-stay, Camping, Sleeper Bus
    transport
    Coach / Bus, Boat, Mini-coach
    operator
    Intrepid Travel
    -10%
    Days
    58
    Our saving
    $540
    From
    $5,395
    US $ 4,855
    days
    58
    $84 per day
    7 Oct 2017 4 spaces left
    14 Oct 2017 4 spaces left
    View MoreGetDownload Brochure
  • Guacamole Ways (from Mexico City)

    47 day discovery tour through Mexico City, Teotihuacan, Oaxaca and 34 other destinations in 7 different countries

    destinations
    44 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    operator
    Bamba Experience
    Days
    47
    Our saving
    $147
    From
    US $ 2,792
    days
    47
    $59 per day
    27 Sep 2017 10 spaces left
    28 Sep 2017 10 spaces left
    View MoreGetDownload Brochure
  • Sofia Ways (from Mexico City)

    38 day hop on/off tour through Mexico City, Teotihuacan, Oaxaca and 22 other destinations in 6 different countries

    destinations
    30 destinations in 6 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    accommodation
    Home-stay
    operator
    Bamba Experience
    Days
    38
    Our saving
    $115
    From
    US $ 2,194
    days
    38
    $58 per day
    27 Sep 2017 10 spaces left
    28 Sep 2017 10 spaces left
    View MoreGetDownload Brochure
  • Limonada Ways (from Mexico City)

    39 day hop on/off tour through Mexico City, Teotihuacan, Oaxaca and 25 other destinations in 7 different countries

    destinations
    34 destinations in 7 countries
    starts/ ends in
    Mexico City / Panama City
    age range
    18 to 99 year olds
    operator
    Bamba Experience
    Days
    39
    Our saving
    $118
    From
    US $ 2,246
    days
    39
    $58 per day
    27 Sep 2017 10 spaces left
    28 Sep 2017 10 spaces left
    View MoreGetDownload Brochure